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Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer.

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Title: Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer.
Authors: Dierick H; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium. herlinde.dierick@vub.be.; Nuclear Medicine Department, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium. herlinde.dierick@vub.be., Navarro L; Precirix NV, Burgemeester Etienne Demunterlaan 3, 1090, Brussels, Belgium., Ceuppens H; Laboratory for Molecular and Cellular Therapy (LCMT), Department of Biomedical Sciences, Translational Oncology Research Center, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building E, 1090, Brussels, Belgium., Ertveldt T; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Laboratory for Molecular and Cellular Therapy (LCMT), Department of Biomedical Sciences, Translational Oncology Research Center, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building E, 1090, Brussels, Belgium., Pombo Antunes AR; Precirix NV, Burgemeester Etienne Demunterlaan 3, 1090, Brussels, Belgium., Keyaerts M; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium., Devoogdt N; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium., Breckpot K; Laboratory for Molecular and Cellular Therapy (LCMT), Department of Biomedical Sciences, Translational Oncology Research Center, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building E, 1090, Brussels, Belgium., D'Huyvetter M; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Precirix NV, Burgemeester Etienne Demunterlaan 3, 1090, Brussels, Belgium., Lahoutte T; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Nuclear Medicine Department, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium., Caveliers V; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Nuclear Medicine Department, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium., Bridoux J; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.
Source: EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2024 Jul 24; Vol. 9 (1), pp. 54. Date of Electronic Publication: 2024 Jul 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer Open Country of Publication: England NLM ID: 101714628 Publication Model: Electronic Cited Medium: Internet ISSN: 2365-421X (Electronic) Linking ISSN: 2365421X NLM ISO Abbreviation: EJNMMI Radiopharm Chem Subsets: PubMed not MEDLINE
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  Data: Generic semi-automated radiofluorination strategy for single domain antibodies: [<superscript>18</superscript>F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer.
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  Data: <searchLink fieldCode="AU" term="%22Dierick+H%22">Dierick H</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium. herlinde.dierick@vub.be.; Nuclear Medicine Department, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium. herlinde.dierick@vub.be.<br /><searchLink fieldCode="AU" term="%22Navarro+L%22">Navarro L</searchLink>; Precirix NV, Burgemeester Etienne Demunterlaan 3, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Ceuppens+H%22">Ceuppens H</searchLink>; Laboratory for Molecular and Cellular Therapy (LCMT), Department of Biomedical Sciences, Translational Oncology Research Center, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building E, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Ertveldt+T%22">Ertveldt T</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Laboratory for Molecular and Cellular Therapy (LCMT), Department of Biomedical Sciences, Translational Oncology Research Center, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building E, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Pombo+Antunes+AR%22">Pombo Antunes AR</searchLink>; Precirix NV, Burgemeester Etienne Demunterlaan 3, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Keyaerts+M%22">Keyaerts M</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Devoogdt+N%22">Devoogdt N</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Breckpot+K%22">Breckpot K</searchLink>; Laboratory for Molecular and Cellular Therapy (LCMT), Department of Biomedical Sciences, Translational Oncology Research Center, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building E, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22D'Huyvetter+M%22">D'Huyvetter M</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Precirix NV, Burgemeester Etienne Demunterlaan 3, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Lahoutte+T%22">Lahoutte T</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Nuclear Medicine Department, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Caveliers+V%22">Caveliers V</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.; Nuclear Medicine Department, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Bridoux+J%22">Bridoux J</searchLink>; Molecular Imaging and Therapy Research Group (MITH), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103. Building K., 1090, Brussels, Belgium.
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