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Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.

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Title: Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.
Authors: Digles D; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria., Ingles-Prieto A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Dvorak V; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Mocking TAM; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands., Goldmann U; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Garofoli A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Homan EJ; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Di Silvio A; Axxam SpA, Bresso, Italy., Azzollini L; Axxam SpA, Bresso, Italy., Sassone F; Axxam SpA, Bresso, Italy., Fogazza M; Axxam SpA, Bresso, Italy., Bärenz F; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany., Pommereau A; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany., Zuschlag Y; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany., Ooms JF; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands., Tranberg-Jensen J; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Hansen JS; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Stanka J; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany., Sijben HJ; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands., Batoulis H; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany., Bender E; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany., Martini R; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria., IJzerman AP; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands., Sauer DB; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Heitman LH; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands., Manolova V; CSL Vifor, StGallen, Switzerland., Reinhardt J; Novartis Pharma AG, Basel, Switzerland., Ehrmann A; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany., Leippe P; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Ecker GF; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria., Huber KVM; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Licher T; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany., Scarabottolo L; Axxam SpA, Bresso, Italy., Wiedmer T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Superti-Furga G; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Source: Frontiers in pharmacology [Front Pharmacol] 2024 Jul 09; Vol. 15, pp. 1401599. Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.
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  Data: <searchLink fieldCode="AU" term="%22Digles+D%22">Digles D</searchLink>; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ingles-Prieto+A%22">Ingles-Prieto A</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Dvorak+V%22">Dvorak V</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Mocking+TAM%22">Mocking TAM</searchLink>; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Goldmann+U%22">Goldmann U</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Garofoli+A%22">Garofoli A</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Homan+EJ%22">Homan EJ</searchLink>; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Di+Silvio+A%22">Di Silvio A</searchLink>; Axxam SpA, Bresso, Italy.<br /><searchLink fieldCode="AU" term="%22Azzollini+L%22">Azzollini L</searchLink>; Axxam SpA, Bresso, Italy.<br /><searchLink fieldCode="AU" term="%22Sassone+F%22">Sassone F</searchLink>; Axxam SpA, Bresso, Italy.<br /><searchLink fieldCode="AU" term="%22Fogazza+M%22">Fogazza M</searchLink>; Axxam SpA, Bresso, Italy.<br /><searchLink fieldCode="AU" term="%22Bärenz+F%22">Bärenz F</searchLink>; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany.<br /><searchLink fieldCode="AU" term="%22Pommereau+A%22">Pommereau A</searchLink>; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany.<br /><searchLink fieldCode="AU" term="%22Zuschlag+Y%22">Zuschlag Y</searchLink>; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany.<br /><searchLink fieldCode="AU" term="%22Ooms+JF%22">Ooms JF</searchLink>; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Tranberg-Jensen+J%22">Tranberg-Jensen J</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hansen+JS%22">Hansen JS</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stanka+J%22">Stanka J</searchLink>; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Sijben+HJ%22">Sijben HJ</searchLink>; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Batoulis+H%22">Batoulis H</searchLink>; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Bender+E%22">Bender E</searchLink>; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Martini+R%22">Martini R</searchLink>; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22IJzerman+AP%22">IJzerman AP</searchLink>; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sauer+DB%22">Sauer DB</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Heitman+LH%22">Heitman LH</searchLink>; Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Manolova+V%22">Manolova V</searchLink>; CSL Vifor, StGallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Reinhardt+J%22">Reinhardt J</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ehrmann+A%22">Ehrmann A</searchLink>; Lead Identification and Characterization, Bayer Pharmaceuticals, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Leippe+P%22">Leippe P</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ecker+GF%22">Ecker GF</searchLink>; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Huber+KVM%22">Huber KVM</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Licher+T%22">Licher T</searchLink>; Sanofi, Integrated Drug Discovery, Industriepark Hoechst, Frankfurt am Main, Hessen, Germany.<br /><searchLink fieldCode="AU" term="%22Scarabottolo+L%22">Scarabottolo L</searchLink>; Axxam SpA, Bresso, Italy.<br /><searchLink fieldCode="AU" term="%22Wiedmer+T%22">Wiedmer T</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Superti-Furga+G%22">Superti-Furga G</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2024 Jul 09; Vol. 15, pp. 1401599. <i>Date of Electronic Publication: </i>2024 Jul 09 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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