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Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19.

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Title: Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19.
Authors: Sidhu JK; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Siggins MK; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Liew F; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Russell CD; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom., Uruchurtu ASS; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Davis C; Medical Research Council Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom., Turtle L; Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom.; Tropical and Infectious Disease Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool Health Partners, Liverpool, United Kingdom., Moore SC; Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom., Hardwick HE; Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom., Oosthuyzen W; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Thomson EC; Medical Research Council Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom.; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom., Semple MG; National Institute for Health and Care Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary, and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.; Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, United Kingdom., Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom., Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Thwaites RS; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Corporate Authors: ISARIC4C investigators
Source: The Journal of infectious diseases [J Infect Dis] 2024 Jul 25; Vol. 230 (1), pp. e17-e29.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Sidhu+JK%22">Sidhu JK</searchLink>; National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Siggins+MK%22">Siggins MK</searchLink>; National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Liew+F%22">Liew F</searchLink>; National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Russell+CD%22">Russell CD</searchLink>; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Uruchurtu+ASS%22">Uruchurtu ASS</searchLink>; National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Davis+C%22">Davis C</searchLink>; Medical Research Council Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Turtle+L%22">Turtle L</searchLink>; Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom.; Tropical and Infectious Disease Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool Health Partners, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Moore+SC%22">Moore SC</searchLink>; Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hardwick+HE%22">Hardwick HE</searchLink>; Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Oosthuyzen+W%22">Oosthuyzen W</searchLink>; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Thomson+EC%22">Thomson EC</searchLink>; Medical Research Council Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom.; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Semple+MG%22">Semple MG</searchLink>; National Institute for Health and Care Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary, and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.; Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Baillie+JK%22">Baillie JK</searchLink>; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Openshaw+PJM%22">Openshaw PJM</searchLink>; National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Thwaites+RS%22">Thwaites RS</searchLink>; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
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