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Methylome-proteome integration after late-life voluntary exercise training reveals regulation and target information for improved skeletal muscle health.

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Title: Methylome-proteome integration after late-life voluntary exercise training reveals regulation and target information for improved skeletal muscle health.
Authors: Chambers TL; Exercise Science Research Center, Molecular Muscle Mass Regulation Laboratory, Department of Health, Human Performance, and Recreation, University of Arkansas, Fayetteville, AR, USA., Dimet-Wiley A; Ridgeline Therapeutics, Houston, TX, USA., Keeble AR; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, USA., Haghani A; Department of Human Genetics, University of California Los Angeles, Los Angeles, CA, USA.; Altos Labs, San Diego, CA, USA., Lo WJ; Department of Educational Statistics and Research Methods, University of Arkansas, Fayetteville, AR, USA., Kang G; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Physiology, University of Kentucky, Lexington, KY, USA.; Division of Biomedical Informatics, Department of Internal Medicine, University of Kentucky, Lexington, KY, USA., Brooke R; Epigenetic Clock Development Foundation, Los Angeles, CA, USA., Horvath S; Department of Human Genetics, University of California Los Angeles, Los Angeles, CA, USA.; Altos Labs, San Diego, CA, USA.; Epigenetic Clock Development Foundation, Los Angeles, CA, USA., Fry CS; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, USA., Watowich SJ; Ridgeline Therapeutics, Houston, TX, USA.; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA., Wen Y; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Physiology, University of Kentucky, Lexington, KY, USA.; Division of Biomedical Informatics, Department of Internal Medicine, University of Kentucky, Lexington, KY, USA., Murach KA; Exercise Science Research Center, Molecular Muscle Mass Regulation Laboratory, Department of Health, Human Performance, and Recreation, University of Arkansas, Fayetteville, AR, USA.
Source: The Journal of physiology [J Physiol] 2025 Jan; Vol. 603 (1), pp. 211-237. Date of Electronic Publication: 2024 Jul 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Methylome-proteome integration after late-life voluntary exercise training reveals regulation and target information for improved skeletal muscle health.
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  Data: <searchLink fieldCode="AU" term="%22Chambers+TL%22">Chambers TL</searchLink>; Exercise Science Research Center, Molecular Muscle Mass Regulation Laboratory, Department of Health, Human Performance, and Recreation, University of Arkansas, Fayetteville, AR, USA.<br /><searchLink fieldCode="AU" term="%22Dimet-Wiley+A%22">Dimet-Wiley A</searchLink>; Ridgeline Therapeutics, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Keeble+AR%22">Keeble AR</searchLink>; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Haghani+A%22">Haghani A</searchLink>; Department of Human Genetics, University of California Los Angeles, Los Angeles, CA, USA.; Altos Labs, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lo+WJ%22">Lo WJ</searchLink>; Department of Educational Statistics and Research Methods, University of Arkansas, Fayetteville, AR, USA.<br /><searchLink fieldCode="AU" term="%22Kang+G%22">Kang G</searchLink>; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Physiology, University of Kentucky, Lexington, KY, USA.; Division of Biomedical Informatics, Department of Internal Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Brooke+R%22">Brooke R</searchLink>; Epigenetic Clock Development Foundation, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Horvath+S%22">Horvath S</searchLink>; Department of Human Genetics, University of California Los Angeles, Los Angeles, CA, USA.; Altos Labs, San Diego, CA, USA.; Epigenetic Clock Development Foundation, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fry+CS%22">Fry CS</searchLink>; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Watowich+SJ%22">Watowich SJ</searchLink>; Ridgeline Therapeutics, Houston, TX, USA.; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wen+Y%22">Wen Y</searchLink>; University of Kentucky Center for Muscle Biology, Lexington, KY, USA.; Department of Physiology, University of Kentucky, Lexington, KY, USA.; Division of Biomedical Informatics, Department of Internal Medicine, University of Kentucky, Lexington, KY, USA.<br /><searchLink fieldCode="AU" term="%22Murach+KA%22">Murach KA</searchLink>; Exercise Science Research Center, Molecular Muscle Mass Regulation Laboratory, Department of Health, Human Performance, and Recreation, University of Arkansas, Fayetteville, AR, USA.
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  Data: <searchLink fieldCode="JN" term="%220266262%22">The Journal of physiology</searchLink> [J Physiol] 2025 Jan; Vol. 603 (1), pp. 211-237. <i>Date of Electronic Publication: </i>2024 Jul 26.
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              Text: 2025 Jan
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