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Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning.

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Title: Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning.
Authors: Estevam GO; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Tetrad Graduate Program, UCSF, San Francisco, CA, United States., Linossi EM; Cardiovascular Research Institute, UCSF, San Francisco, CA, United States.; Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA, United States., Rao J; Department of Computer Science, UCLA, Los Angeles, CA, United States., Macdonald CB; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States., Ravikumar A; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States., Chrispens KM; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Biophysics Graduate Program, UCSF, San Francisco, CA, United States., Capra JA; Bakar Computational Health Sciences Institute and Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, United States., Coyote-Maestas W; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Quantitative Biosciences Institute, UCSF, San Francisco, CA, United States., Pimentel H; Department of Computer Science, UCLA, Los Angeles, CA, United States.; Department of Computational Medicine and Human Genetics, UCLA, Los Angeles, CA, United States.; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States., Collisson EA; Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States.; Department of Medicine, University of Washington, Seattle, Washington, United States., Jura N; Cardiovascular Research Institute, UCSF, San Francisco, CA, United States.; Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA, United States.; Quantitative Biosciences Institute, UCSF, San Francisco, CA, United States., Fraser JS; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Quantitative Biosciences Institute, UCSF, San Francisco, CA, United States.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Dec 05. Date of Electronic Publication: 2024 Dec 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning.
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  Data: <searchLink fieldCode="AU" term="%22Estevam+GO%22">Estevam GO</searchLink>; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Tetrad Graduate Program, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Linossi+EM%22">Linossi EM</searchLink>; Cardiovascular Research Institute, UCSF, San Francisco, CA, United States.; Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Rao+J%22">Rao J</searchLink>; Department of Computer Science, UCLA, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Macdonald+CB%22">Macdonald CB</searchLink>; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ravikumar+A%22">Ravikumar A</searchLink>; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Chrispens+KM%22">Chrispens KM</searchLink>; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Biophysics Graduate Program, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Capra+JA%22">Capra JA</searchLink>; Bakar Computational Health Sciences Institute and Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Coyote-Maestas+W%22">Coyote-Maestas W</searchLink>; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Quantitative Biosciences Institute, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Pimentel+H%22">Pimentel H</searchLink>; Department of Computer Science, UCLA, Los Angeles, CA, United States.; Department of Computational Medicine and Human Genetics, UCLA, Los Angeles, CA, United States.; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Collisson+EA%22">Collisson EA</searchLink>; Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States.; Department of Medicine, University of Washington, Seattle, Washington, United States.<br /><searchLink fieldCode="AU" term="%22Jura+N%22">Jura N</searchLink>; Cardiovascular Research Institute, UCSF, San Francisco, CA, United States.; Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA, United States.; Quantitative Biosciences Institute, UCSF, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Fraser+JS%22">Fraser JS</searchLink>; Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, United States.; Quantitative Biosciences Institute, UCSF, San Francisco, CA, United States.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2024 Dec 05. <i>Date of Electronic Publication: </i>2024 Dec 05.
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        Value: 10.1101/2024.07.16.603579
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              Text: 2024 Dec 05
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