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Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss.

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Title: Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss.
Authors: Chen X; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.; Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China., Chen Z; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.; Department of Otolaryngology Head and Neck Surgery, The 940 Hospital of Joint Logistics Support Force of Chinese PLA, Lanzhou, Gansu Province, China., Li M; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China., Guo W; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China., Yuan S; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China., Xu L; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China., Lin C; Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China., Shi X; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, Hainan Province, China.; Academician Workstation of Hainan University, School of Pharmaceutical Sciences, Yazhou Bay, Sanya, Hainan Province, China., Chen W; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China., Yang S; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.
Source: Neural regeneration research [Neural Regen Res] 2025 May 01; Vol. 20 (5), pp. 1483-1494. Date of Electronic Publication: 2024 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, Medknow Country of Publication: India NLM ID: 101316351 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1673-5374 (Print) Linking ISSN: 16735374 NLM ISO Abbreviation: Neural Regen Res Subsets: PubMed not MEDLINE
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  Data: Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss.
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  Data: <searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.; Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.; Department of Otolaryngology Head and Neck Surgery, The 940 Hospital of Joint Logistics Support Force of Chinese PLA, Lanzhou, Gansu Province, China.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Guo+W%22">Guo W</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yuan+S%22">Yuan S</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, Hainan Province, China.; Academician Workstation of Hainan University, School of Pharmaceutical Sciences, Yazhou Bay, Sanya, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Chen+W%22">Chen W</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.; State Key Laboratory of Hearing and Balance Science, Beijing, China.; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.; Key Laboratory of Hearing Science, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing, China.
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  Data: <searchLink fieldCode="JN" term="%22101316351%22">Neural regeneration research</searchLink> [Neural Regen Res] 2025 May 01; Vol. 20 (5), pp. 1483-1494. <i>Date of Electronic Publication: </i>2024 Jun 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Medknow%22">Wolters Kluwer Health, Medknow </searchLink><i>Country of Publication: </i>India <i>NLM ID: </i>101316351 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1673-5374 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216735374%22">16735374 </searchLink><i>NLM ISO Abbreviation: </i>Neural Regen Res <i>Subsets: </i>PubMed not MEDLINE
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RecordInfo BibRecord:
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        Value: 10.4103/NRR.NRR-D-24-00130
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      – Code: eng
        Text: English
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      – TitleFull: Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss.
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              Text: 2025 May 01
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