Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.

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Title: Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.
Authors: Perez Garcia G; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States., Bicak M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Buros J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Haure-Mirande JV; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Perez GM; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States., Otero-Pagan A; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States., Gama Sosa MA; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States., De Gasperi R; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Sano M; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Gage FH; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA, United States.; BrainCells, Inc., La Jolla, CA, United States., Barlow C; BrainCells, Inc., La Jolla, CA, United States.; E-Scape Bio, South San Francisco, CA, United States., Dudley JT; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Glicksberg BS; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Wang Y; Department of Developmental and Cell Biology, University of Michigan, Ann Arbor, MI, United States., Readhead B; Arizona State University-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, United States., Ehrlich ME; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Elder GA; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY, United States., Gandy S; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Mount Sinai Center for Cognitive Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Source: Frontiers in dementia [Front Dement] 2023 Sep 06; Vol. 2, pp. 1198006. Date of Electronic Publication: 2023 Sep 06 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 9918787575706676 Publication Model: eCollection Cited Medium: Internet ISSN: 2813-3919 (Electronic) Linking ISSN: 28133919 NLM ISO Abbreviation: Front Dement Subsets: PubMed not MEDLINE
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  Data: Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.
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  Data: <searchLink fieldCode="AU" term="%22Perez+Garcia+G%22">Perez Garcia G</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.<br /><searchLink fieldCode="AU" term="%22Bicak+M%22">Bicak M</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Buros+J%22">Buros J</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Haure-Mirande+JV%22">Haure-Mirande JV</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Perez+GM%22">Perez GM</searchLink>; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.<br /><searchLink fieldCode="AU" term="%22Otero-Pagan+A%22">Otero-Pagan A</searchLink>; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.<br /><searchLink fieldCode="AU" term="%22Gama+Sosa+MA%22">Gama Sosa MA</searchLink>; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22De+Gasperi+R%22">De Gasperi R</searchLink>; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Sano+M%22">Sano M</searchLink>; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Gage+FH%22">Gage FH</searchLink>; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA, United States.; BrainCells, Inc., La Jolla, CA, United States.<br /><searchLink fieldCode="AU" term="%22Barlow+C%22">Barlow C</searchLink>; BrainCells, Inc., La Jolla, CA, United States.; E-Scape Bio, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Dudley+JT%22">Dudley JT</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Glicksberg+BS%22">Glicksberg BS</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Developmental and Cell Biology, University of Michigan, Ann Arbor, MI, United States.<br /><searchLink fieldCode="AU" term="%22Readhead+B%22">Readhead B</searchLink>; Arizona State University-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, United States.<br /><searchLink fieldCode="AU" term="%22Ehrlich+ME%22">Ehrlich ME</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Elder+GA%22">Elder GA</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY, United States.<br /><searchLink fieldCode="AU" term="%22Gandy+S%22">Gandy S</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Research and Development, James J. Peters Veterans Affairs Medical Center, Bronx, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Mount Sinai Center for Cognitive Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
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        Value: 10.3389/frdem.2023.1198006
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