Conditional loss of Brca1 in oocytes causes reduced litter size, ovarian reserve depletion and impaired oocyte in vitro maturation with advanced reproductive age in mice.

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Title: Conditional loss of Brca1 in oocytes causes reduced litter size, ovarian reserve depletion and impaired oocyte in vitro maturation with advanced reproductive age in mice.
Authors: Winship AL; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia. Electronic address: amy.winship@monash.edu., Alesi LR; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Stringer JM; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Cao Y; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Lewis YM; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Tu L; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Swindells EOK; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Giridharan S; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Cai X; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Griffiths MJ; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia; University of Edinburgh, MRC Centre for Reproductive Health, Queens Medical Research Institute, Edinburgh, UK., Zerafa N; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia., Gilham L; Breast Cancer Network Australia and Breast Cancer Trials Australia, Camberwell, VIC, Australia., Hickey M; Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia; Department of Obstetrics and Gynaecology, The University of Melbourne, Parkville, VIC, Australia., Hutt KJ; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia. Electronic address: karla.hutt@monash.edu.
Source: EBioMedicine [EBioMedicine] 2024 Aug; Vol. 106, pp. 105262. Date of Electronic Publication: 2024 Jul 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: Conditional loss of Brca1 in oocytes causes reduced litter size, ovarian reserve depletion and impaired oocyte in vitro maturation with advanced reproductive age in mice.
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  Data: <searchLink fieldCode="AU" term="%22Winship+AL%22">Winship AL</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia. Electronic address: amy.winship@monash.edu.<br /><searchLink fieldCode="AU" term="%22Alesi+LR%22">Alesi LR</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Stringer+JM%22">Stringer JM</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Cao+Y%22">Cao Y</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Lewis+YM%22">Lewis YM</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Tu+L%22">Tu L</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Swindells+EOK%22">Swindells EOK</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Giridharan+S%22">Giridharan S</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Cai+X%22">Cai X</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Griffiths+MJ%22">Griffiths MJ</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia; University of Edinburgh, MRC Centre for Reproductive Health, Queens Medical Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Zerafa+N%22">Zerafa N</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Gilham+L%22">Gilham L</searchLink>; Breast Cancer Network Australia and Breast Cancer Trials Australia, Camberwell, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hickey+M%22">Hickey M</searchLink>; Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC, Australia; Department of Obstetrics and Gynaecology, The University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hutt+KJ%22">Hutt KJ</searchLink>; Monash Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Development and Stem Cells Program, Monash University, Clayton, VIC, Australia. Electronic address: karla.hutt@monash.edu.
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  Data: <searchLink fieldCode="JN" term="%22101647039%22">EBioMedicine</searchLink> [EBioMedicine] 2024 Aug; Vol. 106, pp. 105262. <i>Date of Electronic Publication: </i>2024 Jul 30.
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