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Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: Findings from the LACE sarcopenia trial.

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Title: Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: Findings from the LACE sarcopenia trial.
Authors: Shrestha A; Cardiovascular and Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom.; Cutrale Perioperative and Ageing Group, Department of Bioengineering, Imperial College London, London, United Kingdom., Bashir T; Cardiovascular and Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom., Achison M; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Adamson S; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Akpan A; Liverpool University Hospitals NHS FT Trust, Clinical Research Network Northwest Coast, University of Liverpool, Liverpool, United Kingdom., Aspray T; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Translational Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Avenell A; Health Services Research Unit, University of Aberdeen, Aberdeen, United Kingdom., Band MM; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Burton LA; Medicine for the Elderly, NHS Tayside, Dundee, United Kingdom.; Ageing and Health, University of Dundee, Dundee, United Kingdom., Cvoro V; Victoria Hospital, Kirkcaldy, United Kingdom.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Donnan PT; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom., Duncan GW; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; Medicine for the Elderly, NHS Lothian, Edinburgh, United Kingdom., George J; Division of Molecular & Clinical Medicine, University of Dundee Medical School, Ninewells Hospital, Dundee, United Kingdom., Gordon AL; Unit of Injury, Inflammation and Recovery, School of Medicine, University of Nottingham, Nottingham United Kingdom.; NIHR Nottingham Biomedical Research Centre, Department of Medicine for the Elderly, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom., Gregson CL; Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Older Person's Unit, Royal United Hospital NHS Foundation Trust Bath, Bath, United Kingdom., Hapca A; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Hume C; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Jackson TA; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom., Kerr S; Department of Older People's Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Kilgour A; Medicine for the Elderly, NHS Lothian, Edinburgh, United Kingdom.; Ageing and Health Research Group, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom., Masud T; Clinical Gerontology Research Unit, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, United Kingdom., McKenzie A; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., McKenzie E; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Patel H; NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHSFT, Southampton, Hampshire, United Kingdom., Pilvinyte K; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Roberts HC; Academic Geriatric Medicine, Mailpoint 807 Southampton General Hospital, University of Southampton, Southampton, United Kingdom., Sayer AA; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Translational Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Rossios C; Cardiovascular and Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom., Smith KT; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom., Soiza RL; Ageing & Clinical Experimental Research (ACER) Group, University of Aberdeen, Aberdeen, United Kingdom., Steves CJ; Department of Twin Research and Genetic Epidemiology, King's College London & Department of Clinical Gerontology, King's College Hospital, London, United Kingdom., Struthers AD; Division of Molecular & Clinical Medicine, University of Dundee Medical School, Ninewells Hospital, Dundee, United Kingdom., Tiwari D; Bournemouth University and Royal Bournemouth Hospital, Bournemouth, United Kingdom., Whitney J; School of Population Health & Environmental Sciences, King's College London and King's College Hospital, London, United Kingdom., Witham MD; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Translational Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Kemp PR; Cardiovascular and Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom.
Source: PloS one [PLoS One] 2024 Aug 02; Vol. 19 (8), pp. e0307268. Date of Electronic Publication: 2024 Aug 02 (Print Publication: 2024).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: Findings from the LACE sarcopenia trial.
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Liverpool University Hospitals NHS FT Trust, Clinical Research Network Northwest Coast, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Aspray+T%22">Aspray T</searchLink>; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Translational Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Avenell+A%22">Avenell A</searchLink>; Health Services Research Unit, University of Aberdeen, Aberdeen, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Band+MM%22">Band MM</searchLink>; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Burton+LA%22">Burton LA</searchLink>; Medicine for the Elderly, NHS Tayside, Dundee, United Kingdom.; 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Department of Older People's Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kilgour+A%22">Kilgour A</searchLink>; Medicine for the Elderly, NHS Lothian, Edinburgh, United Kingdom.; Ageing and Health Research Group, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Masud+T%22">Masud T</searchLink>; Clinical Gerontology Research Unit, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McKenzie+A%22">McKenzie A</searchLink>; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McKenzie+E%22">McKenzie E</searchLink>; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Patel+H%22">Patel H</searchLink>; NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHSFT, Southampton, Hampshire, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pilvinyte+K%22">Pilvinyte K</searchLink>; Tayside Clinical Trials Unit (TCTU), Tayside Medical Science Centre (TASC), Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Roberts+HC%22">Roberts HC</searchLink>; Academic Geriatric Medicine, Mailpoint 807 Southampton General Hospital, University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sayer+AA%22">Sayer AA</searchLink>; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Trust, Translational Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rossios+C%22">Rossios C</searchLink>; 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