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The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas.

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Title: The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas.
Authors: Deng J; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.; Clinical Research Centre (CRC), Medical Pathology Centre (MPC), Cancer Early Detection and Treatment Centre (CEDTC), Translational Medicine Research Centre (TMRC), Chongqing University Three Gorges Hospital, Chongqing University, Wanzhou, Chongqing, China., Pan T; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.; Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), 518172, Shenzhen, China., Wang D; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Hong Y; Digestive Oncology Unit and Centre for Human Genetics, Universitair Ziekenhuis (UZ) Leuven, Leuven, Belgium., Liu Z; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Zhou X; Department of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing, China., An Z; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Li L; Internet Medical and System Applications of National Engineering Laboratory, Zhengzhou, China., Alfano G; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Li G; Department of General Surgery, Peking University Third Hospital, Beijing, China., Dolcetti L; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Evans R; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Vicencio JM; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Vlckova P; Cell Communication Lab, UCL Cancer Institute, 72 Huntley Street, London, WC1E 6DD, UK., Chen Y; Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK., Monypenny J; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Gomes CAC; UCL Cancer Institute, University College London, London, UK., Weitsman G; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Ng K; Department of Medical Oncology, University College London Hospitals NHS Foundation Trust, London, UK., McCarthy C; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Yang X; Centre of Excellence for Mass Spectrometry, Proteomics Facility, The James Black Centre, King's College London, London, UK., Hu Z; Digestive Oncology Unit and Centre for Human Genetics, Universitair Ziekenhuis (UZ) Leuven, Leuven, Belgium., Porter JC; Centre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College London (UCL), Rayne Building, London, UK., Tape CJ; Cell Communication Lab, UCL Cancer Institute, 72 Huntley Street, London, WC1E 6DD, UK., Yin M; Clinical Research Centre (CRC), Medical Pathology Centre (MPC), Cancer Early Detection and Treatment Centre (CEDTC), Translational Medicine Research Centre (TMRC), Chongqing University Three Gorges Hospital, Chongqing University, Wanzhou, Chongqing, China., Wei F; Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), 518172, Shenzhen, China., Rodriguez-Justo M; Department of Histopathology, University College London Hospital, London, UK., Zhang J; 3rd Department of Breast Cancer Prevention, Treatment and Research Centre, Tianjin, PR China.; Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin, PR China.; Tianjin's Clinical Research Centre for Cancer, Tianjin, PR China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China.; National Clinical Research Centre for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, PR China., Tejpar S; Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), 518172, Shenzhen, China., Beatson R; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK. r.beatson@ucl.ac.uk.; Centre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College London (UCL), Rayne Building, London, UK. r.beatson@ucl.ac.uk.; Centre for the Tumour Microenvironment, Barts Cancer Institute, Queen Mary University of London, London, UK. r.beatson@ucl.ac.uk., Ng T; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK. tony.ng@kcl.ac.uk.; UCL Cancer Institute, University College London, London, UK. tony.ng@kcl.ac.uk.; Cancer Research UK City of London Centre, London, UK. tony.ng@kcl.ac.uk.
Source: EMBO molecular medicine [EMBO Mol Med] 2024 Sep; Vol. 16 (9), pp. 2080-2108. Date of Electronic Publication: 2024 Aug 05.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas.
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  Data: <searchLink fieldCode="AU" term="%22Deng+J%22">Deng J</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.; Clinical Research Centre (CRC), Medical Pathology Centre (MPC), Cancer Early Detection and Treatment Centre (CEDTC), Translational Medicine Research Centre (TMRC), Chongqing University Three Gorges Hospital, Chongqing University, Wanzhou, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Pan+T%22">Pan T</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.; Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), 518172, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hong+Y%22">Hong Y</searchLink>; Digestive Oncology Unit and Centre for Human Genetics, Universitair Ziekenhuis (UZ) Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Department of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22An+Z%22">An Z</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Internet Medical and System Applications of National Engineering Laboratory, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Alfano+G%22">Alfano G</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; Department of General Surgery, Peking University Third Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Dolcetti+L%22">Dolcetti L</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Evans+R%22">Evans R</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Vicencio+JM%22">Vicencio JM</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Vlckova+P%22">Vlckova P</searchLink>; Cell Communication Lab, UCL Cancer Institute, 72 Huntley Street, London, WC1E 6DD, UK.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Monypenny+J%22">Monypenny J</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gomes+CAC%22">Gomes CAC</searchLink>; UCL Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Weitsman+G%22">Weitsman G</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ng+K%22">Ng K</searchLink>; Department of Medical Oncology, University College London Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22McCarthy+C%22">McCarthy C</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Centre of Excellence for Mass Spectrometry, Proteomics Facility, The James Black Centre, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hu+Z%22">Hu Z</searchLink>; Digestive Oncology Unit and Centre for Human Genetics, Universitair Ziekenhuis (UZ) Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Porter+JC%22">Porter JC</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College London (UCL), Rayne Building, London, UK.<br /><searchLink fieldCode="AU" term="%22Tape+CJ%22">Tape CJ</searchLink>; Cell Communication Lab, UCL Cancer Institute, 72 Huntley Street, London, WC1E 6DD, UK.<br /><searchLink fieldCode="AU" term="%22Yin+M%22">Yin M</searchLink>; Clinical Research Centre (CRC), Medical Pathology Centre (MPC), Cancer Early Detection and Treatment Centre (CEDTC), Translational Medicine Research Centre (TMRC), Chongqing University Three Gorges Hospital, Chongqing University, Wanzhou, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wei+F%22">Wei F</searchLink>; Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), 518172, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Justo+M%22">Rodriguez-Justo M</searchLink>; Department of Histopathology, University College London Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; 3rd Department of Breast Cancer Prevention, Treatment and Research Centre, Tianjin, PR China.; Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin, PR China.; Tianjin's Clinical Research Centre for Cancer, Tianjin, PR China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China.; National Clinical Research Centre for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, PR China.<br /><searchLink fieldCode="AU" term="%22Tejpar+S%22">Tejpar S</searchLink>; Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), 518172, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Beatson+R%22">Beatson R</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK. r.beatson@ucl.ac.uk.; Centre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College London (UCL), Rayne Building, London, UK. r.beatson@ucl.ac.uk.; Centre for the Tumour Microenvironment, Barts Cancer Institute, Queen Mary University of London, London, UK. r.beatson@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ng+T%22">Ng T</searchLink>; Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK. tony.ng@kcl.ac.uk.; UCL Cancer Institute, University College London, London, UK. tony.ng@kcl.ac.uk.; Cancer Research UK City of London Centre, London, UK. tony.ng@kcl.ac.uk.
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