Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.

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Title: Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.
Authors: Stubbs BJ; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA. Electronic address: bstubbs@buckinstitute.org., Stephens EB; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Senadheera C; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Peralta S; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Roa-Diaz S; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Alexander L; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Silverman-Martin W; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Garcia TY; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA., Yukawa M; Division of Geriatrics, UCSF, 3575 Geary Blvd, Fl 1, San Francisco, CA 94118-3212, USA; Geriatrics, San Francisco VA Medical Center, 4150 Clement St, San Francisco, CA 94121-1563, USA., Morris J; Geriatrics, San Francisco VA Medical Center, 4150 Clement St, San Francisco, CA 94121-1563, USA., Blonquist TM; Biofortis, Mérieux NutriSciences, 800-A South Rohling Rd, Addison, IL 60101-4219, USA., Johnson JB; Independent Researcher, Greenbrae, CA, USA., Newman JC; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA; Division of Geriatrics, UCSF, 3575 Geary Blvd, Fl 1, San Francisco, CA 94118-3212, USA. Electronic address: jnewman@buckinstitute.org.
Source: The journal of nutrition, health & aging [J Nutr Health Aging] 2024 Sep; Vol. 28 (9), pp. 100329. Date of Electronic Publication: 2024 Aug 12.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Masson SAS on behalf of SERDI Publisher Country of Publication: France NLM ID: 100893366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1760-4788 (Electronic) Linking ISSN: 12797707 NLM ISO Abbreviation: J Nutr Health Aging Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.
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  Data: <searchLink fieldCode="AU" term="%22Stubbs+BJ%22">Stubbs BJ</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA. Electronic address: bstubbs@buckinstitute.org.<br /><searchLink fieldCode="AU" term="%22Stephens+EB%22">Stephens EB</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Senadheera+C%22">Senadheera C</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Peralta+S%22">Peralta S</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Roa-Diaz+S%22">Roa-Diaz S</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Alexander+L%22">Alexander L</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Silverman-Martin+W%22">Silverman-Martin W</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+TY%22">Garcia TY</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA.<br /><searchLink fieldCode="AU" term="%22Yukawa+M%22">Yukawa M</searchLink>; Division of Geriatrics, UCSF, 3575 Geary Blvd, Fl 1, San Francisco, CA 94118-3212, USA; Geriatrics, San Francisco VA Medical Center, 4150 Clement St, San Francisco, CA 94121-1563, USA.<br /><searchLink fieldCode="AU" term="%22Morris+J%22">Morris J</searchLink>; Geriatrics, San Francisco VA Medical Center, 4150 Clement St, San Francisco, CA 94121-1563, USA.<br /><searchLink fieldCode="AU" term="%22Blonquist+TM%22">Blonquist TM</searchLink>; Biofortis, Mérieux NutriSciences, 800-A South Rohling Rd, Addison, IL 60101-4219, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+JB%22">Johnson JB</searchLink>; Independent Researcher, Greenbrae, CA, USA.<br /><searchLink fieldCode="AU" term="%22Newman+JC%22">Newman JC</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945-1400, USA; Division of Geriatrics, UCSF, 3575 Geary Blvd, Fl 1, San Francisco, CA 94118-3212, USA. Electronic address: jnewman@buckinstitute.org.
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  Data: <searchLink fieldCode="JN" term="%22100893366%22">The journal of nutrition, health & aging</searchLink> [J Nutr Health Aging] 2024 Sep; Vol. 28 (9), pp. 100329. <i>Date of Electronic Publication: </i>2024 Aug 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Masson+SAS+on+behalf+of+SERDI+Publisher%22">Elsevier Masson SAS on behalf of SERDI Publisher </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>100893366 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1760-4788 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2212797707%22">12797707 </searchLink><i>NLM ISO Abbreviation: </i>J Nutr Health Aging <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jnha.2024.100329
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      – TitleFull: Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.
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