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Emerging therapeutics: The imidazo[1,2-b]pyridazine scaffold as a novel drug candidate for eumycetoma, a neglected tropical disease.

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Title: Emerging therapeutics: The imidazo[1,2-b]pyridazine scaffold as a novel drug candidate for eumycetoma, a neglected tropical disease.
Authors: Elkheir LYM; The Mycetoma Research Center, University of Khartoum, Khartoum, Sudan; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, Sudan; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France., Delaye PO; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France., Penichon M; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France., Eadie K; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, University of Rotterdam, the Netherlands., Mohamed MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, KSA, Saudi Arabia., Besson P; UMR INSERM U1327 ISCHEMIA 'Membrane signalling and inflammation in reperfusion injuries', University of Tours, France., Chesnay A; UMR INSERM U 1100 Centre d'Etudes des Pathologies Respiratoires, University of Tours, France., Desoubeaux G; UMR INSERM U 1100 Centre d'Etudes des Pathologies Respiratoires, University of Tours, France., Roger S; UMR INSERM U1327 ISCHEMIA 'Membrane signalling and inflammation in reperfusion injuries', University of Tours, France., van de Sande WWJ; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, University of Rotterdam, the Netherlands., Fahal AH; The Mycetoma Research Center, University of Khartoum, Khartoum, Sudan., Enguehard-Gueiffier C; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France. Electronic address: cecile.gueiffier@univ-tours.fr.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Nov 05; Vol. 277, pp. 116720. Date of Electronic Publication: 2024 Jul 26.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
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  Data: Emerging therapeutics: The imidazo[1,2-b]pyridazine scaffold as a novel drug candidate for eumycetoma, a neglected tropical disease.
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  Data: <searchLink fieldCode="AU" term="%22Elkheir+LYM%22">Elkheir LYM</searchLink>; The Mycetoma Research Center, University of Khartoum, Khartoum, Sudan; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, Sudan; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France.<br /><searchLink fieldCode="AU" term="%22Delaye+PO%22">Delaye PO</searchLink>; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France.<br /><searchLink fieldCode="AU" term="%22Penichon+M%22">Penichon M</searchLink>; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France.<br /><searchLink fieldCode="AU" term="%22Eadie+K%22">Eadie K</searchLink>; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, University of Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mohamed+MA%22">Mohamed MA</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, KSA, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Besson+P%22">Besson P</searchLink>; UMR INSERM U1327 ISCHEMIA 'Membrane signalling and inflammation in reperfusion injuries', University of Tours, France.<br /><searchLink fieldCode="AU" term="%22Chesnay+A%22">Chesnay A</searchLink>; UMR INSERM U 1100 Centre d'Etudes des Pathologies Respiratoires, University of Tours, France.<br /><searchLink fieldCode="AU" term="%22Desoubeaux+G%22">Desoubeaux G</searchLink>; UMR INSERM U 1100 Centre d'Etudes des Pathologies Respiratoires, University of Tours, France.<br /><searchLink fieldCode="AU" term="%22Roger+S%22">Roger S</searchLink>; UMR INSERM U1327 ISCHEMIA 'Membrane signalling and inflammation in reperfusion injuries', University of Tours, France.<br /><searchLink fieldCode="AU" term="%22van+de+Sande+WWJ%22">van de Sande WWJ</searchLink>; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, University of Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Fahal+AH%22">Fahal AH</searchLink>; The Mycetoma Research Center, University of Khartoum, Khartoum, Sudan.<br /><searchLink fieldCode="AU" term="%22Enguehard-Gueiffier+C%22">Enguehard-Gueiffier C</searchLink>; EA 7502 Synthèse et Isolement de Molécules Bioactives (SIMBA), University of Tours, France. Electronic address: cecile.gueiffier@univ-tours.fr.
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  Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2024 Nov 05; Vol. 277, pp. 116720. <i>Date of Electronic Publication: </i>2024 Jul 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE
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