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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.

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Title: The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.
Authors: Pölönen P; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Di Giacomo D; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy., Seffernick AE; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN, USA., Elsayed A; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN, USA., Kimura S; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Benini F; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Research Hospital, Rome, Italy., Montefiori LE; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Wood BL; Children's Hospital Los Angeles, Laboratory Medicine, Los Angeles, CA, USA., Xu J; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Chen C; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Cheng Z; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Newman H; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Myers J; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Iacobucci I; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Li E; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Sussman J; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hedges D; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Hui Y; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Diorio C; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Uppuluri L; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Frank D; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fan Y; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Chang Y; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Meshinchi S; Fred Hutchinson Cancer Research Center, Clinical Research Division, Seattle, WA, USA., Ries R; Fred Hutchinson Cancer Research Center, Clinical Research Division, Seattle, WA, USA., Shraim R; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Li A; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Bernt KM; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Devidas M; Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN, USA., Winter SS; Research Institute and Cancer and Blood Disorders Program, Children's Minnesota, Minneapolis, MN, USA., Dunsmore KP; Division of Oncology, University of Virginia Children's Hospital, Charlottesville, VA, USA., Inaba H; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA., Carroll WL; Division of Pediatric Hematology Oncology, Department of Pediatrics, NYU Langone Health, New York, NY, USA.; Department of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Ramirez NC; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA., Phillips AH; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Kriwacki RW; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN, USA., Yang JJ; Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN, USA., Vincent TL; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Zhao Y; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Ghate PS; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Wang J; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Reilly C; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Zhou X; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, TN, USA., Sanders MA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Takita J; Department of Pediatrics, Graduate School of Medicine Kyoto University, Kyoto, Japan., Kato M; Department of Pediatrics, Tokyo University, Tokyo, Japan., Takasugi N; Department of Pediatrics, Tokyo University, Tokyo, Japan., Chang BH; Department of Pediatrics, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA., Press RD; Department of Pathology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA., Loh M; Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA, USA., Rampersaud E; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Raetz E; Division of Pediatric Hematology Oncology, Department of Pediatrics, NYU Langone Health, New York, NY, USA.; Department of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Hunger SP; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Tan K; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Center for Single Cell Biology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Chang TC; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Wu G; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA., Pounds SB; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN, USA., Mullighan CG; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA. charles.mullighan@stjude.org., Teachey DT; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. teacheyd@chop.edu.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA. teacheyd@chop.edu.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA. teacheyd@chop.edu.
Source: Nature [Nature] 2024 Aug; Vol. 632 (8027), pp. 1082-1091. Date of Electronic Publication: 2024 Aug 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.
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  Data: <searchLink fieldCode="AU" term="%22Pölönen+P%22">Pölönen P</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Di+Giacomo+D%22">Di Giacomo D</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Seffernick+AE%22">Seffernick AE</searchLink>; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Elsayed+A%22">Elsayed A</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Kimura+S%22">Kimura S</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Benini+F%22">Benini F</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Research Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Montefiori+LE%22">Montefiori LE</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wood+BL%22">Wood BL</searchLink>; Children's Hospital Los Angeles, Laboratory Medicine, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+Z%22">Cheng Z</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Newman+H%22">Newman H</searchLink>; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Myers+J%22">Myers J</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Iacobucci+I%22">Iacobucci I</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Li+E%22">Li E</searchLink>; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sussman+J%22">Sussman J</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hedges+D%22">Hedges D</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Hui+Y%22">Hui Y</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Diorio+C%22">Diorio C</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Uppuluri+L%22">Uppuluri L</searchLink>; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Frank+D%22">Frank D</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chang+Y%22">Chang Y</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Meshinchi+S%22">Meshinchi S</searchLink>; Fred Hutchinson Cancer Research Center, Clinical Research Division, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ries+R%22">Ries R</searchLink>; Fred Hutchinson Cancer Research Center, Clinical Research Division, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Shraim+R%22">Shraim R</searchLink>; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bernt+KM%22">Bernt KM</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Devidas+M%22">Devidas M</searchLink>; Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Winter+SS%22">Winter SS</searchLink>; Research Institute and Cancer and Blood Disorders Program, Children's Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Dunsmore+KP%22">Dunsmore KP</searchLink>; Division of Oncology, University of Virginia Children's Hospital, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Inaba+H%22">Inaba H</searchLink>; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Carroll+WL%22">Carroll WL</searchLink>; Division of Pediatric Hematology Oncology, Department of Pediatrics, NYU Langone Health, New York, NY, USA.; Department of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez+NC%22">Ramirez NC</searchLink>; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Phillips+AH%22">Phillips AH</searchLink>; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Kriwacki+RW%22">Kriwacki RW</searchLink>; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Yang+JJ%22">Yang JJ</searchLink>; Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Vincent+TL%22">Vincent TL</searchLink>; 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Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Takita+J%22">Takita J</searchLink>; Department of Pediatrics, Graduate School of Medicine Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+M%22">Kato M</searchLink>; Department of Pediatrics, Tokyo University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takasugi+N%22">Takasugi N</searchLink>; Department of Pediatrics, Tokyo University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Chang+BH%22">Chang BH</searchLink>; Department of Pediatrics, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Press+RD%22">Press RD</searchLink>; Department of Pathology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Loh+M%22">Loh M</searchLink>; Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rampersaud+E%22">Rampersaud E</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Raetz+E%22">Raetz E</searchLink>; Division of Pediatric Hematology Oncology, Department of Pediatrics, NYU Langone Health, New York, NY, USA.; Department of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hunger+SP%22">Hunger SP</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tan+K%22">Tan K</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Center for Single Cell Biology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chang+TC%22">Chang TC</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wu+G%22">Wu G</searchLink>; Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Pounds+SB%22">Pounds SB</searchLink>; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Mullighan+CG%22">Mullighan CG</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA. charles.mullighan@stjude.org.<br /><searchLink fieldCode="AU" term="%22Teachey+DT%22">Teachey DT</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. teacheyd@chop.edu.; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA. teacheyd@chop.edu.; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA. teacheyd@chop.edu.
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          Name:
            NameFull: Takita J
      – PersonEntity:
          Name:
            NameFull: Kato M
      – PersonEntity:
          Name:
            NameFull: Takasugi N
      – PersonEntity:
          Name:
            NameFull: Chang BH
      – PersonEntity:
          Name:
            NameFull: Press RD
      – PersonEntity:
          Name:
            NameFull: Loh M
      – PersonEntity:
          Name:
            NameFull: Rampersaud E
      – PersonEntity:
          Name:
            NameFull: Raetz E
      – PersonEntity:
          Name:
            NameFull: Hunger SP
      – PersonEntity:
          Name:
            NameFull: Tan K
      – PersonEntity:
          Name:
            NameFull: Chang TC
      – PersonEntity:
          Name:
            NameFull: Wu G
      – PersonEntity:
          Name:
            NameFull: Pounds SB
      – PersonEntity:
          Name:
            NameFull: Mullighan CG
      – PersonEntity:
          Name:
            NameFull: Teachey DT
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Text: 2024 Aug
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1476-4687
          Numbering:
            – Type: volume
              Value: 632
            – Type: issue
              Value: 8027
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1