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Structure and inhibition of SARS-CoV-2 spike refolding in membranes.

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Title: Structure and inhibition of SARS-CoV-2 spike refolding in membranes.
Authors: Grunst MW; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA., Qin Z; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA., Dodero-Rojas E; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA., Ding S; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada., Prévost J; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada., Chen Y; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4712, USA., Hu Y; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA., Pazgier M; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4712, USA., Wu S; Department of Pharmacology, Yale University, West Haven, CT 06516, USA., Xie X; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA., Finzi A; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada., Onuchic JN; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Physics and Astronomy, Rice University, Houston, TX, USA.; Department of Chemistry, Rice University, Houston, TX, USA.; Department of Biosciences, Rice University, Houston, TX, USA., Whitford PC; Center for Theoretical Biological Physics, Northeastern University, Boston, MA, USA.; Department of Physics, Northeastern University, Boston, MA, USA., Mothes W; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA., Li W; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA.
Source: Science (New York, N.Y.) [Science] 2024 Aug 16; Vol. 385 (6710), pp. 757-765. Date of Electronic Publication: 2024 Aug 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structure and inhibition of SARS-CoV-2 spike refolding in membranes.
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  Data: <searchLink fieldCode="AU" term="%22Grunst+MW%22">Grunst MW</searchLink>; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Qin+Z%22">Qin Z</searchLink>; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Dodero-Rojas+E%22">Dodero-Rojas E</searchLink>; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ding+S%22">Ding S</searchLink>; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.<br /><searchLink fieldCode="AU" term="%22Prévost+J%22">Prévost J</searchLink>; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4712, USA.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Pazgier+M%22">Pazgier M</searchLink>; Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4712, USA.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Department of Pharmacology, Yale University, West Haven, CT 06516, USA.<br /><searchLink fieldCode="AU" term="%22Xie+X%22">Xie X</searchLink>; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Finzi+A%22">Finzi A</searchLink>; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada.<br /><searchLink fieldCode="AU" term="%22Onuchic+JN%22">Onuchic JN</searchLink>; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Physics and Astronomy, Rice University, Houston, TX, USA.; Department of Chemistry, Rice University, Houston, TX, USA.; Department of Biosciences, Rice University, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Whitford+PC%22">Whitford PC</searchLink>; Center for Theoretical Biological Physics, Northeastern University, Boston, MA, USA.; Department of Physics, Northeastern University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mothes+W%22">Mothes W</searchLink>; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Microbial Pathogenesis, Yale University, New Haven, CT, USA.
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