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In vitro and in vivo evaluation of Bombesin-MMAE conjugates for targeted tumour therapy.

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Title: In vitro and in vivo evaluation of Bombesin-MMAE conjugates for targeted tumour therapy.
Authors: Gomena J; Hevesy György PhD School of Chemistry, Eötvös Loránd University, 1117, Budapest, Hungary; Eötvös Loránd University, Faculty of Science, Institute of Chemistry, 1117, Budapest, Hungary; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117, Budapest, Hungary., Modena D; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy., Cordella P; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy., Vári B; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085, Budapest, Hungary., Ranđelović I; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary; KINETO Lab Ltd., 1037, Budapest, Hungary., Borbély A; MTA-ELTE Lendület Ion Mobility Mass Spectrometry Research Group, 1117, Budapest, Hungary., Bottani M; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy., Vári-Mező D; Eötvös Loránd University, Faculty of Science, Institute of Chemistry, 1117, Budapest, Hungary; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117, Budapest, Hungary; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085, Budapest, Hungary., Halmos G; Department of Biopharmacy, Faculty of Pharmacy, University of Debrecen, 4032, Debrecen, Hungary., Juhász É; Department of Pediatrics, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary., Steinkühler C; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy., Tóvári J; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary., Mező G; Eötvös Loránd University, Faculty of Science, Institute of Chemistry, 1117, Budapest, Hungary; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117, Budapest, Hungary. Electronic address: gabor.mezo@ttk.elte.hu.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Nov 05; Vol. 277, pp. 116767. Date of Electronic Publication: 2024 Aug 13.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In vitro and in vivo evaluation of Bombesin-MMAE conjugates for targeted tumour therapy.
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  Data: <searchLink fieldCode="AU" term="%22Gomena+J%22">Gomena J</searchLink>; Hevesy György PhD School of Chemistry, Eötvös Loránd University, 1117, Budapest, Hungary; Eötvös Loránd University, Faculty of Science, Institute of Chemistry, 1117, Budapest, Hungary; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Modena+D%22">Modena D</searchLink>; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Cordella+P%22">Cordella P</searchLink>; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Vári+B%22">Vári B</searchLink>; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Ranđelović+I%22">Ranđelović I</searchLink>; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary; KINETO Lab Ltd., 1037, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Borbély+A%22">Borbély A</searchLink>; MTA-ELTE Lendület Ion Mobility Mass Spectrometry Research Group, 1117, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Bottani+M%22">Bottani M</searchLink>; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Vári-Mező+D%22">Vári-Mező D</searchLink>; Eötvös Loránd University, Faculty of Science, Institute of Chemistry, 1117, Budapest, Hungary; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117, Budapest, Hungary; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Halmos+G%22">Halmos G</searchLink>; Department of Biopharmacy, Faculty of Pharmacy, University of Debrecen, 4032, Debrecen, Hungary.<br /><searchLink fieldCode="AU" term="%22Juhász+É%22">Juhász É</searchLink>; Department of Pediatrics, Faculty of Medicine, University of Debrecen, 4032, Debrecen, Hungary.<br /><searchLink fieldCode="AU" term="%22Steinkühler+C%22">Steinkühler C</searchLink>; Italfarmaco S.p.A., Preclinical R&D Department, 20092, Cinisello Balsamo (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Tóvári+J%22">Tóvári J</searchLink>; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Mező+G%22">Mező G</searchLink>; Eötvös Loránd University, Faculty of Science, Institute of Chemistry, 1117, Budapest, Hungary; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117, Budapest, Hungary. Electronic address: gabor.mezo@ttk.elte.hu.
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  Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2024 Nov 05; Vol. 277, pp. 116767. <i>Date of Electronic Publication: </i>2024 Aug 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE
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