Angong Niuhuang Wan ameliorates LPS-induced cerebrovascular edema by inhibiting blood‒brain barrier leakage and promoting the membrane expression of AQP4.

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Title: Angong Niuhuang Wan ameliorates LPS-induced cerebrovascular edema by inhibiting blood‒brain barrier leakage and promoting the membrane expression of AQP4.
Authors: Liu BT; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Li Q; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Sun K; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Pan CS; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Huo XM; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Huang P; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Yan L; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., He QH; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China., Zhong LJ; Peking University Medical and Health Analysis Center, Peking University, Beijing, China., Wang Y; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China., Hu ML; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Li AQ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Jiao YQ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Zhang S; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Wang XY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Liu J; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Han JY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2024 Aug 01; Vol. 15, pp. 1421635. Date of Electronic Publication: 2024 Aug 01 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Label: Title
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  Data: Angong Niuhuang Wan ameliorates LPS-induced cerebrovascular edema by inhibiting blood‒brain barrier leakage and promoting the membrane expression of AQP4.
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  Data: <searchLink fieldCode="AU" term="%22Liu+BT%22">Liu BT</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sun+K%22">Sun K</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Pan+CS%22">Pan CS</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huo+XM%22">Huo XM</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+P%22">Huang P</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22He+QH%22">He QH</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhong+LJ%22">Zhong LJ</searchLink>; Peking University Medical and Health Analysis Center, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Hu+ML%22">Hu ML</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+AQ%22">Li AQ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jiao+YQ%22">Jiao YQ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Han+JY%22">Han JY</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2024 Aug 01; Vol. 15, pp. 1421635. <i>Date of Electronic Publication: </i>2024 Aug 01 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: Angong Niuhuang Wan ameliorates LPS-induced cerebrovascular edema by inhibiting blood‒brain barrier leakage and promoting the membrane expression of AQP4.
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