Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
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| Title: | Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer. |
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| Authors: | Sun X; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA., Ferguson JA; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA., Yang K; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA., Stanfield RL; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA., Dyson HJ; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA., Wright PE; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA. |
| Source: | Protein science : a publication of the Protein Society [Protein Sci] 2024 Sep; Vol. 33 (9), pp. e5101. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39149996 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+JA%22">Ferguson JA</searchLink>; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Yang+K%22">Yang K</searchLink>; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Stanfield+RL%22">Stanfield RL</searchLink>; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Dyson+HJ%22">Dyson HJ</searchLink>; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Wright+PE%22">Wright PE</searchLink>; Department of Integrative Structural and Computational Biology and Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, California, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229211750%22">Protein science : a publication of the Protein Society</searchLink> [Protein Sci] 2024 Sep; Vol. 33 (9), pp. e5101. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cold+Spring+Harbor+Laboratory+Press%22">Cold Spring Harbor Laboratory Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9211750 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1469-896X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209618368%22">09618368 </searchLink><i>NLM ISO Abbreviation: </i>Protein Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39149996 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/pro.5101 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e5101 Titles: – TitleFull: Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sun X – PersonEntity: Name: NameFull: Ferguson JA – PersonEntity: Name: NameFull: Yang K – PersonEntity: Name: NameFull: Stanfield RL – PersonEntity: Name: NameFull: Dyson HJ – PersonEntity: Name: NameFull: Wright PE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2024 Sep Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1469-896X Numbering: – Type: volume Value: 33 – Type: issue Value: 9 Titles: – TitleFull: Protein science : a publication of the Protein Society Type: main |
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