Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract.

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Title: Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract.
Authors: Ewing LE; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Skinner CM; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA., McGill MR; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Kennon-McGill S; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Clement K; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Quick CM; Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Yee EU; Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Williams DK; Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Arkansas Children's Nutrition Center, Little Rock, AR, USA., Walker LA; National Center for Natural Products Research, University of Mississippi, University, MS, USA.; ElSohly Laboratories, Inc. (ELI), Oxford, MS, USA., ElSohly MA; National Center for Natural Products Research, University of Mississippi, University, MS, USA.; ElSohly Laboratories, Inc. (ELI), Oxford, MS, USA., Gurley BJ; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Arkansas Children's Nutrition Center, Little Rock, AR, USA., Koturbash I; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Source: Drug and chemical toxicology [Drug Chem Toxicol] 2025 May; Vol. 48 (3), pp. 578-585. Date of Electronic Publication: 2024 Aug 19.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6014 (Electronic) Linking ISSN: 01480545 NLM ISO Abbreviation: Drug Chem Toxicol Subsets: MEDLINE
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  Data: Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract.
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  Data: <searchLink fieldCode="AU" term="%22Ewing+LE%22">Ewing LE</searchLink>; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Skinner+CM%22">Skinner CM</searchLink>; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22McGill+MR%22">McGill MR</searchLink>; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Kennon-McGill+S%22">Kennon-McGill S</searchLink>; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Clement+K%22">Clement K</searchLink>; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Quick+CM%22">Quick CM</searchLink>; Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Yee+EU%22">Yee EU</searchLink>; Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Williams+DK%22">Williams DK</searchLink>; Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Arkansas Children's Nutrition Center, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Walker+LA%22">Walker LA</searchLink>; National Center for Natural Products Research, University of Mississippi, University, MS, USA.; ElSohly Laboratories, Inc. (ELI), Oxford, MS, USA.<br /><searchLink fieldCode="AU" term="%22ElSohly+MA%22">ElSohly MA</searchLink>; National Center for Natural Products Research, University of Mississippi, University, MS, USA.; ElSohly Laboratories, Inc. (ELI), Oxford, MS, USA.<br /><searchLink fieldCode="AU" term="%22Gurley+BJ%22">Gurley BJ</searchLink>; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Arkansas Children's Nutrition Center, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Koturbash+I%22">Koturbash I</searchLink>; Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Center for Dietary Supplements Research, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
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