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Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson's disease: pooled analysis of patient level data from two randomized open-label studies.

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Title: Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson's disease: pooled analysis of patient level data from two randomized open-label studies.
Authors: Ferreira JJ; IMM - Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. jferreira@medicina.ulisboa.pt.; CNS - Campus Neurológico, Torres Vedras, Portugal. jferreira@medicina.ulisboa.pt., Lee JY; Department of Neurology, SMG-SNU Boramae Medical Center, Seoul, Korea., Ma HI; Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea., Jeon B; Department of Neurology, Seoul National University Hospital, Seoul, Korea., Poewe W; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Antonini A; Department of Neurosciences, University of Padova, Padua, Italy., Stocchi F; University San Raffaele Roma and Institute for Research and Medical Care IRCCS San Raffaele, Rome, Italy., Rodrigues DM; BIAL - Portela and Ca S.A., Coronado, Portugal., Fonseca MM; BIAL - R&D Investments, S.A., Coronado, Portugal., Castilla-Fernández G; BIAL - R&D Investments, S.A., Coronado, Portugal., Holenz J; BIAL - Portela and Ca S.A., Coronado, Portugal., Rocha JF; BIAL - Portela and Ca S.A., Coronado, Portugal., Rascol O; Clinical Investigation Center CIC1436, Departments of Neurosciences and Clinical Pharmacology and NS-Park/FCRIN Network, University of Toulouse 3, University Hospital of Toulouse, INSERM, Toulouse, France.
Corporate Authors: ADOPTION study investigators
Source: Journal of neurology [J Neurol] 2024 Oct; Vol. 271 (10), pp. 6729-6738. Date of Electronic Publication: 2024 Aug 21.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson's disease: pooled analysis of patient level data from two randomized open-label studies.
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  Data: <searchLink fieldCode="AU" term="%22Ferreira+JJ%22">Ferreira JJ</searchLink>; IMM - Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. jferreira@medicina.ulisboa.pt.; CNS - Campus Neurológico, Torres Vedras, Portugal. jferreira@medicina.ulisboa.pt.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Neurology, SMG-SNU Boramae Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Ma+HI%22">Ma HI</searchLink>; Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+B%22">Jeon B</searchLink>; Department of Neurology, Seoul National University Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Poewe+W%22">Poewe W</searchLink>; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Antonini+A%22">Antonini A</searchLink>; Department of Neurosciences, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Stocchi+F%22">Stocchi F</searchLink>; University San Raffaele Roma and Institute for Research and Medical Care IRCCS San Raffaele, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rodrigues+DM%22">Rodrigues DM</searchLink>; BIAL - Portela and Ca S.A., Coronado, Portugal.<br /><searchLink fieldCode="AU" term="%22Fonseca+MM%22">Fonseca MM</searchLink>; BIAL - R&D Investments, S.A., Coronado, Portugal.<br /><searchLink fieldCode="AU" term="%22Castilla-Fernández+G%22">Castilla-Fernández G</searchLink>; BIAL - R&D Investments, S.A., Coronado, Portugal.<br /><searchLink fieldCode="AU" term="%22Holenz+J%22">Holenz J</searchLink>; BIAL - Portela and Ca S.A., Coronado, Portugal.<br /><searchLink fieldCode="AU" term="%22Rocha+JF%22">Rocha JF</searchLink>; BIAL - Portela and Ca S.A., Coronado, Portugal.<br /><searchLink fieldCode="AU" term="%22Rascol+O%22">Rascol O</searchLink>; Clinical Investigation Center CIC1436, Departments of Neurosciences and Clinical Pharmacology and NS-Park/FCRIN Network, University of Toulouse 3, University Hospital of Toulouse, INSERM, Toulouse, France.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0423161 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1459 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203405354%22">03405354 </searchLink><i>NLM ISO Abbreviation: </i>J Neurol <i>Subsets: </i>MEDLINE
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              Text: 2024 Oct
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