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Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor.

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Title: Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor.
Authors: Mpakali A; National Centre for Scientific Research Demokritos, Athens, Greece.; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece., Georgaki G; National Centre for Scientific Research Demokritos, Athens, Greece.; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece., Buson A; Syntara Limited, Sydney, New South Wales, Australia., Findlay AD; Syntara Limited, Sydney, New South Wales, Australia., Foot JS; Syntara Limited, Sydney, New South Wales, Australia., Mauvais FX; INSERM, CNRS, Institut Necker Enfants Malades, Université Paris Cité, Paris, France., van Endert P; INSERM, CNRS, Institut Necker Enfants Malades, Université Paris Cité, Paris, France., Giastas P; Department of Biotechnology, School of Applied Biology & Biotechnology, Agricultural University of Athens, Athens, Greece., Hamprecht DW; Syntara Limited, Sydney, New South Wales, Australia., Stratikos E; National Centre for Scientific Research Demokritos, Athens, Greece.; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.
Source: Protein science : a publication of the Protein Society [Protein Sci] 2024 Sep; Vol. 33 (9), pp. e5151.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor.
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  Data: <searchLink fieldCode="AU" term="%22Mpakali+A%22">Mpakali A</searchLink>; National Centre for Scientific Research Demokritos, Athens, Greece.; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Georgaki+G%22">Georgaki G</searchLink>; National Centre for Scientific Research Demokritos, Athens, Greece.; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Buson+A%22">Buson A</searchLink>; Syntara Limited, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Findlay+AD%22">Findlay AD</searchLink>; Syntara Limited, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Foot+JS%22">Foot JS</searchLink>; Syntara Limited, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Mauvais+FX%22">Mauvais FX</searchLink>; INSERM, CNRS, Institut Necker Enfants Malades, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22van+Endert+P%22">van Endert P</searchLink>; INSERM, CNRS, Institut Necker Enfants Malades, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Giastas+P%22">Giastas P</searchLink>; Department of Biotechnology, School of Applied Biology & Biotechnology, Agricultural University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Hamprecht+DW%22">Hamprecht DW</searchLink>; Syntara Limited, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Stratikos+E%22">Stratikos E</searchLink>; National Centre for Scientific Research Demokritos, Athens, Greece.; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cold+Spring+Harbor+Laboratory+Press%22">Cold Spring Harbor Laboratory Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9211750 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1469-896X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209618368%22">09618368 </searchLink><i>NLM ISO Abbreviation: </i>Protein Sci <i>Subsets: </i>MEDLINE
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              Text: 2024 Sep
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