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The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA.

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Title: The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA.
Authors: Hengel SR; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA. sarah.hengel@tufts.edu.; Tufts University, Department of Biology, Medford, MA, USA. sarah.hengel@tufts.edu., Oppenheimer KG; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA., Smith CM; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.; University of North Carolina at Chapel Hill, Department of Pathology and Laboratory Medicine, Chapel Hill, NC, USA., Schaich MA; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA., Rein HL; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA., Martino J; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.; GeneDx, Gaithersburg, MD, USA., Darrah KE; University of Pennsylvania School of Medicine, Penn Center for Genome Integrity, Department of Biochemistry and Biophysics, 421 Curie Boulevard, Philadelphia, PA, USA., Witham M; Tufts University, Department of Biology, Medford, MA, USA., Ezekwenna OC; Tufts University, Department of Biology, Medford, MA, USA., Burton KR; Tufts University, Department of Biology, Medford, MA, USA., Van Houten B; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA., Spies M; University of Iowa, Department of Biochemistry and Molecular Biology, Iowa City, IA, USA., Bernstein KA; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA. kara.bernstein@pennmedicine.upenn.edu.; University of Pennsylvania School of Medicine, Penn Center for Genome Integrity, Department of Biochemistry and Biophysics, 421 Curie Boulevard, Philadelphia, PA, USA. kara.bernstein@pennmedicine.upenn.edu.
Source: Nature communications [Nat Commun] 2024 Aug 21; Vol. 15 (1), pp. 7197. Date of Electronic Publication: 2024 Aug 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hengel+SR%22">Hengel SR</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA. sarah.hengel@tufts.edu.; Tufts University, Department of Biology, Medford, MA, USA. sarah.hengel@tufts.edu.<br /><searchLink fieldCode="AU" term="%22Oppenheimer+KG%22">Oppenheimer KG</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+CM%22">Smith CM</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.; University of North Carolina at Chapel Hill, Department of Pathology and Laboratory Medicine, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Schaich+MA%22">Schaich MA</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Rein+HL%22">Rein HL</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Martino+J%22">Martino J</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.; GeneDx, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Darrah+KE%22">Darrah KE</searchLink>; University of Pennsylvania School of Medicine, Penn Center for Genome Integrity, Department of Biochemistry and Biophysics, 421 Curie Boulevard, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Witham+M%22">Witham M</searchLink>; Tufts University, Department of Biology, Medford, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ezekwenna+OC%22">Ezekwenna OC</searchLink>; Tufts University, Department of Biology, Medford, MA, USA.<br /><searchLink fieldCode="AU" term="%22Burton+KR%22">Burton KR</searchLink>; Tufts University, Department of Biology, Medford, MA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Houten+B%22">Van Houten B</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Spies+M%22">Spies M</searchLink>; University of Iowa, Department of Biochemistry and Molecular Biology, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Bernstein+KA%22">Bernstein KA</searchLink>; University of Pittsburgh, School of Medicine, Department of Pharmacology and Chemical Biology, UPMC-Hillman Cancer Center, Pittsburgh, PA, USA. kara.bernstein@pennmedicine.upenn.edu.; University of Pennsylvania School of Medicine, Penn Center for Genome Integrity, Department of Biochemistry and Biophysics, 421 Curie Boulevard, Philadelphia, PA, USA. kara.bernstein@pennmedicine.upenn.edu.
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