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MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.

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Title: MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.
Authors: Khanal R; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany., Heinen N; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Bogomolova A; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany., Meister TL; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Institute for Infection Research and Vaccine Development (IIRVD), Centre for Internal Medicine, University Medical Centre Hamburg-Eppendorf (UKE), Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany., Herrmann ST; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany., Westhoven S; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany., Nocke MK; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Todt D; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; European Virus Bioinformatics Center (EVBC), Jena, Germany., Jockenhövel F; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Klein IM; Tissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Hartmann L; Tissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Vondran FWR; Department of General, Visceral, Pediatric and Transplant Surgery, University Hospital RWTH Aachen, Aachen, Germany., Steinmann E; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Zimmer G; Institute of Virology and Immunology, Bern, Switzerland.; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Ott M; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Brown RJP; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Sharma AD; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany., Pfaender S; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany.; University of Lübeck, Lübeck, Germany.
Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Nov; Vol. 44 (11), pp. 2983-2995. Date of Electronic Publication: 2024 Aug 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.
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  Data: <searchLink fieldCode="AU" term="%22Khanal+R%22">Khanal R</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Heinen+N%22">Heinen N</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Bogomolova+A%22">Bogomolova A</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Meister+TL%22">Meister TL</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Institute for Infection Research and Vaccine Development (IIRVD), Centre for Internal Medicine, University Medical Centre Hamburg-Eppendorf (UKE), Hamburg, Germany.; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Herrmann+ST%22">Herrmann ST</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Westhoven+S%22">Westhoven S</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nocke+MK%22">Nocke MK</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Todt+D%22">Todt D</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; European Virus Bioinformatics Center (EVBC), Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Jockenhövel+F%22">Jockenhövel F</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Klein+IM%22">Klein IM</searchLink>; Tissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+L%22">Hartmann L</searchLink>; Tissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Vondran+FWR%22">Vondran FWR</searchLink>; Department of General, Visceral, Pediatric and Transplant Surgery, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Steinmann+E%22">Steinmann E</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Zimmer+G%22">Zimmer G</searchLink>; Institute of Virology and Immunology, Bern, Switzerland.; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ott+M%22">Ott M</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Brown+RJP%22">Brown RJP</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Sharma+AD%22">Sharma AD</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Research Group Liver Regeneration & RNA Therapeutics, REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Pfaender+S%22">Pfaender S</searchLink>; Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.; Research Unit Emerging Viruses, Leibniz Institute of Virology (LIV), Hamburg, Germany.; University of Lübeck, Lübeck, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101160857%22">Liver international : official journal of the International Association for the Study of the Liver</searchLink> [Liver Int] 2024 Nov; Vol. 44 (11), pp. 2983-2995. <i>Date of Electronic Publication: </i>2024 Aug 22.
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