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In pancreatic cancer patients, chemotherapy reshapes the gene expression profile and antigen receptor repertoire of T lymphocytes and enhances their effector response to tumor-associated antigens.

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Title: In pancreatic cancer patients, chemotherapy reshapes the gene expression profile and antigen receptor repertoire of T lymphocytes and enhances their effector response to tumor-associated antigens.
Authors: Brugiapaglia S; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.; Molecular Biotechnology Center 'Guido Tarone', University of Turin, Turin, Italy., Bulfamante S; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Curcio C; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.; Molecular Biotechnology Center 'Guido Tarone', University of Turin, Turin, Italy., Arigoni M; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Calogero R; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Bonello L; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Genuardi E; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Spadi R; Centro Oncologico Ematologico Subalpino, Azienda Ospedaliera Universitaria (A.O.U.) Città della Salute e della Scienza di Torino, Turin, Italy., Satolli MA; Centro Oncologico Ematologico Subalpino, Azienda Ospedaliera Universitaria (A.O.U.) Città della Salute e della Scienza di Torino, Turin, Italy., Campra D; Struttura Complessa (SC) Chirurgia generale d'urgenza e pronto soccorso, Azienda Ospedaliera Universitaria (A.O.U.) Città della Salute e della Scienza di Torino, Turin, Italy., Giordano D; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Cappello P; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.; Molecular Biotechnology Center 'Guido Tarone', University of Turin, Turin, Italy., Cordero F; Computer Science Department, University of Turin, Turin, Italy., Novelli F; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.; Molecular Biotechnology Center 'Guido Tarone', University of Turin, Turin, Italy.
Source: Frontiers in immunology [Front Immunol] 2024 Aug 08; Vol. 15, pp. 1427424. Date of Electronic Publication: 2024 Aug 08 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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