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Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease.

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Title: Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease.
Authors: Chandler JC; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Jafree DJ; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.; UCL MB/PhD Programme, Faculty of Medical Sciences, University College London, London, UK., Malik S; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Pomeranz G; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Ball M; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Kolatsi-Joannou M; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Piapi A; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK., Mason WJ; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Benest AV; Endothelial Quiescence Group and Tumour and Vascular Biology Laboratories, Division of Cancer and Stem Cells, Centre for Cancer Sciences, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Bates DO; Endothelial Quiescence Group and Tumour and Vascular Biology Laboratories, Division of Cancer and Stem Cells, Centre for Cancer Sciences, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK.; Pan-African Cancer Research Institute, University of Pretoria, Hatfield, South Africa., Letunovska A; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Al-Saadi R; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Rabant M; Pathology department, Hôpital Universitaire Necker-Enfants Malades, Institut Imagine, Université Paris Cité, Paris, France., Boyer O; APHP, Service de Néphrologie Pédiatrique, Hôpital Universitaire Necker-Enfants Malades, Institut Imagine, Université Paris Cité, Paris, France., Pritchard-Jones K; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK., Winyard PJ; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK., Mason AS; Department of Biology and York Biomedical Research Institute, University of York, UK., Woolf AS; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Waters AM; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK., Long DA; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.
Source: The Journal of pathology [J Pathol] 2024 Oct; Vol. 264 (2), pp. 212-227. Date of Electronic Publication: 2024 Aug 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
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  Data: Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease.
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  Data: <searchLink fieldCode="AU" term="%22Chandler+JC%22">Chandler JC</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Jafree+DJ%22">Jafree DJ</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.; UCL MB/PhD Programme, Faculty of Medical Sciences, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Malik+S%22">Malik S</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Pomeranz+G%22">Pomeranz G</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Ball+M%22">Ball M</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Kolatsi-Joannou+M%22">Kolatsi-Joannou M</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Piapi+A%22">Piapi A</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Mason+WJ%22">Mason WJ</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Benest+AV%22">Benest AV</searchLink>; Endothelial Quiescence Group and Tumour and Vascular Biology Laboratories, Division of Cancer and Stem Cells, Centre for Cancer Sciences, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Bates+DO%22">Bates DO</searchLink>; Endothelial Quiescence Group and Tumour and Vascular Biology Laboratories, Division of Cancer and Stem Cells, Centre for Cancer Sciences, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK.; Pan-African Cancer Research Institute, University of Pretoria, Hatfield, South Africa.<br /><searchLink fieldCode="AU" term="%22Letunovska+A%22">Letunovska A</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Al-Saadi+R%22">Al-Saadi R</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Rabant+M%22">Rabant M</searchLink>; Pathology department, Hôpital Universitaire Necker-Enfants Malades, Institut Imagine, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Boyer+O%22">Boyer O</searchLink>; APHP, Service de Néphrologie Pédiatrique, Hôpital Universitaire Necker-Enfants Malades, Institut Imagine, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pritchard-Jones+K%22">Pritchard-Jones K</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Winyard+PJ%22">Winyard PJ</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Mason+AS%22">Mason AS</searchLink>; Department of Biology and York Biomedical Research Institute, University of York, UK.<br /><searchLink fieldCode="AU" term="%22Woolf+AS%22">Woolf AS</searchLink>; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Waters+AM%22">Waters AM</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Long+DA%22">Long DA</searchLink>; Developmental Biology and Cancer Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK.; UCL Centre for Kidney and Bladder Health, London, UK.
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