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SGLT2 inhibition improves PI3Kα inhibitor-induced hyperglycemia: findings from preclinical animal models and from patients in the BYLieve and SOLAR-1 trials.

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Title: SGLT2 inhibition improves PI3Kα inhibitor-induced hyperglycemia: findings from preclinical animal models and from patients in the BYLieve and SOLAR-1 trials.
Authors: Borrego MR; Hospital Universitario Virgen del Rocío de Sevilla, Seville, Spain. ruizsabater@gmail.com., Lu YS; National Taiwan University Hospital, Taipei, Taiwan., Reyes-Cosmelli F; Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile., Park YH; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Yamashita T; Kanagawa Cancer Center, Yokohama, Japan., Chiu J; Queen Mary Hospital, Pok Fu Lam, Hong Kong., Airoldi M; Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy., Turner N; The Royal Marsden NHS Foundation Trust, London, UK., Fein L; Instituto de Oncología de Rosario, Santa Fe, Argentina., Ghaznawi F; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA., Singh J; Novartis Healthcare Private Ltd, Hyderabad, India., Pantoja K; Novartis Pharmaceuticals Corporation, Cambridge, MA, USA., Schnell C; Novartis Pharma AG, Basel, Switzerland., Akdere M; Novartis Pharma AG, Basel, Switzerland., Chia S; BC Cancer, Vancouver, BC, Canada.
Source: Breast cancer research and treatment [Breast Cancer Res Treat] 2024 Nov; Vol. 208 (1), pp. 111-121. Date of Electronic Publication: 2024 Aug 23.
Publication Type: Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SGLT2 inhibition improves PI3Kα inhibitor-induced hyperglycemia: findings from preclinical animal models and from patients in the BYLieve and SOLAR-1 trials.
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  Data: <searchLink fieldCode="AU" term="%22Borrego+MR%22">Borrego MR</searchLink>; Hospital Universitario Virgen del Rocío de Sevilla, Seville, Spain. ruizsabater@gmail.com.<br /><searchLink fieldCode="AU" term="%22Lu+YS%22">Lu YS</searchLink>; National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Reyes-Cosmelli+F%22">Reyes-Cosmelli F</searchLink>; Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Park+YH%22">Park YH</searchLink>; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Yamashita+T%22">Yamashita T</searchLink>; Kanagawa Cancer Center, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Chiu+J%22">Chiu J</searchLink>; Queen Mary Hospital, Pok Fu Lam, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Airoldi+M%22">Airoldi M</searchLink>; Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Turner+N%22">Turner N</searchLink>; The Royal Marsden NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Fein+L%22">Fein L</searchLink>; Instituto de Oncología de Rosario, Santa Fe, Argentina.<br /><searchLink fieldCode="AU" term="%22Ghaznawi+F%22">Ghaznawi F</searchLink>; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Singh+J%22">Singh J</searchLink>; Novartis Healthcare Private Ltd, Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Pantoja+K%22">Pantoja K</searchLink>; Novartis Pharmaceuticals Corporation, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schnell+C%22">Schnell C</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Akdere+M%22">Akdere M</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chia+S%22">Chia S</searchLink>; BC Cancer, Vancouver, BC, Canada.
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  Data: <searchLink fieldCode="JN" term="%228111104%22">Breast cancer research and treatment</searchLink> [Breast Cancer Res Treat] 2024 Nov; Vol. 208 (1), pp. 111-121. <i>Date of Electronic Publication: </i>2024 Aug 23.
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  Data: Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%22">Kluwer Academic </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8111104 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7217 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201676806%22">01676806 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res Treat <i>Subsets: </i>MEDLINE
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              Text: 2024 Nov
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