The extensive m5C epitranscriptome of Thermococcus kodakarensis is generated by a suite of RNA methyltransferases that support thermophily. - Fluke KA; Fuchs RT; Tsai YL; Talbott V; Elkins L; Febvre HP; Dai N; Wolf EJ; Burkhart BW; Schiltz J; Brett Robb G; Corrêa IR Jr; et al. (Nature communications, 2024)