Engineered minimal type I CRISPR-Cas system for transcriptional activation and base editing in human cells.
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| Title: | Engineered minimal type I CRISPR-Cas system for transcriptional activation and base editing in human cells. |
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| Authors: | Guo J; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; College of Life Science, University of Chinese Academy of Sciences, Beijing, China., Gong L; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. gongly@im.ac.cn., Yu H; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Li M; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; College of Life Science, University of Chinese Academy of Sciences, Beijing, China., An Q; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; College of Life Science, University of Chinese Academy of Sciences, Beijing, China., Liu Z; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; College of Life Science, University of Chinese Academy of Sciences, Beijing, China., Fan S; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Yang C; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; College of Life Science, University of Chinese Academy of Sciences, Beijing, China., Zhao D; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Han J; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Xiang H; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. xiangh@im.ac.cn.; College of Life Science, University of Chinese Academy of Sciences, Beijing, China. xiangh@im.ac.cn.; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China. xiangh@im.ac.cn. |
| Source: | Nature communications [Nat Commun] 2024 Aug 23; Vol. 15 (1), pp. 7277. Date of Electronic Publication: 2024 Aug 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-51695-x |
