TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells.
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| Title: | TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells. |
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| Authors: | Truong P; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Shen S; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Joshi S; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Islam MI; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Zhong L; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Raftery MJ; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Afrasiabi A; UNSW BioMedical Machine Learning Lab (BML), The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia., Alinejad-Rokny H; UNSW BioMedical Machine Learning Lab (BML), The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.; Tyree Institute of Health Engineering (IHealthE), UNSW Sydney, Sydney, NSW, Australia., Nguyen M; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Zou X; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Bhuyan GS; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Sarowar CH; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Ghodousi ES; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Stonehouse O; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Mohamed S; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Toscan CE; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Connerty P; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Kakadia PM; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Bohlander SK; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Michie KA; Structural Biology Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Larsson J; Division of Molecular Medicine and Gene Therapy, Lund Stem Cell Centre, Lund University, Lund, Sweden., Lock RB; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Walkley CR; St Vincent's Institute of Medical Research, University of Melbourne, Melbourne, VIC, Australia.; Department of Medicine, University of Melbourne, Melbourne, VIC, Australia., Thoms JAI; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Jolly CJ; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia. c.jolly@unsw.edu.au., Pimanda JE; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia. jpimanda@unsw.edu.au.; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia. jpimanda@unsw.edu.au.; Haematology Department, Prince of Wales Hospital, Sydney, NSW, Australia. jpimanda@unsw.edu.au. |
| Source: | Nature communications [Nat Commun] 2024 Aug 28; Vol. 15 (1), pp. 7360. Date of Electronic Publication: 2024 Aug 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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