Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17.
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| Title: | Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17. |
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| Authors: | Bachhav N; College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, WA 99202, USA., Singh DK; College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, WA 99202, USA., Blithe DL; Contraceptive Development Program, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 1 Center Dr, Bethesda, MD 20892, USA., Lee MS; Contraceptive Development Program, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 1 Center Dr, Bethesda, MD 20892, USA., Prasad B; College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, WA 99202, USA. |
| Source: | Pharmaceutics [Pharmaceutics] 2024 Aug 02; Vol. 16 (8). Date of Electronic Publication: 2024 Aug 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39204377 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bachhav+N%22">Bachhav N</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, WA 99202, USA.<br /><searchLink fieldCode="AU" term="%22Singh+DK%22">Singh DK</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, WA 99202, USA.<br /><searchLink fieldCode="AU" term="%22Blithe+DL%22">Blithe DL</searchLink>; Contraceptive Development Program, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 1 Center Dr, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Lee+MS%22">Lee MS</searchLink>; Contraceptive Development Program, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 1 Center Dr, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Prasad+B%22">Prasad B</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, WA 99202, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101534003%22">Pharmaceutics</searchLink> [Pharmaceutics] 2024 Aug 02; Vol. 16 (8). <i>Date of Electronic Publication: </i>2024 Aug 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101534003 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1999-4923 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219994923%22">19994923 </searchLink><i>NLM ISO Abbreviation: </i>Pharmaceutics <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39204377 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/pharmaceutics16081032 Languages: – Code: eng Text: English Titles: – TitleFull: Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bachhav N – PersonEntity: Name: NameFull: Singh DK – PersonEntity: Name: NameFull: Blithe DL – PersonEntity: Name: NameFull: Lee MS – PersonEntity: Name: NameFull: Prasad B IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 08 Text: 2024 Aug 02 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 1999-4923 Numbering: – Type: volume Value: 16 – Type: issue Value: 8 Titles: – TitleFull: Pharmaceutics Type: main |
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