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STING Agonist Induced Innate Immune Responses Drive Anti-Respiratory Virus Activity In Vitro with Limited Antiviral Efficacy In Vivo.

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Title: STING Agonist Induced Innate Immune Responses Drive Anti-Respiratory Virus Activity In Vitro with Limited Antiviral Efficacy In Vivo.
Authors: Broeckel R; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States., Browne A; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States., Sucoloski S; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States., Cantizani J; Global Health Medicines R&D, GSK R&D, Tres Cantos, Madrid 28760, Spain., Simpson JK; Target Discovery Research Projects, GSK R&D, Stevenage SG1 2NY, United Kingdom., Pesiridis S; Immunology Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States., Ramanjulu JM; Immunology Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States., Stokes N; Infectious Diseases Research Unit, GSK R&D, Stevenage SG1 2NY, United Kingdom., Luthra P; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.
Source: ACS infectious diseases [ACS Infect Dis] 2024 Sep 13; Vol. 10 (9), pp. 3392-3407. Date of Electronic Publication: 2024 Aug 29.
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: STING Agonist Induced Innate Immune Responses Drive Anti-Respiratory Virus Activity In Vitro with Limited Antiviral Efficacy In Vivo.
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  Data: <searchLink fieldCode="AU" term="%22Broeckel+R%22">Broeckel R</searchLink>; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.<br /><searchLink fieldCode="AU" term="%22Browne+A%22">Browne A</searchLink>; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.<br /><searchLink fieldCode="AU" term="%22Sucoloski+S%22">Sucoloski S</searchLink>; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.<br /><searchLink fieldCode="AU" term="%22Cantizani+J%22">Cantizani J</searchLink>; Global Health Medicines R&D, GSK R&D, Tres Cantos, Madrid 28760, Spain.<br /><searchLink fieldCode="AU" term="%22Simpson+JK%22">Simpson JK</searchLink>; Target Discovery Research Projects, GSK R&D, Stevenage SG1 2NY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pesiridis+S%22">Pesiridis S</searchLink>; Immunology Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.<br /><searchLink fieldCode="AU" term="%22Ramanjulu+JM%22">Ramanjulu JM</searchLink>; Immunology Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.<br /><searchLink fieldCode="AU" term="%22Stokes+N%22">Stokes N</searchLink>; Infectious Diseases Research Unit, GSK R&D, Stevenage SG1 2NY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Luthra+P%22">Luthra P</searchLink>; Infectious Diseases Research Unit, GSK R&D, Collegeville, Pennsylvania 19426, United States.
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        Value: 10.1021/acsinfecdis.4c00504
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        Text: English
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              Text: 2024 Sep 13
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