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Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.

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Title: Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.
Authors: Solé-Navais P; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden. pol.sole.navais@gu.se., Juodakis J; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden., Ytterberg K; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden., Wu X; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Copenhagen University Hospital Biobank Unit, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark., Bradfield JP; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Quantinuum Research LLC, Wayne, PA, USA., Vaudel M; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., LaBella AL; Department of Bioinformatics and Genomics, College of Computing and Informatics, North Carolina Research Campus, University of North Carolina at Charlotte, Kannapolis, NC, USA., Helgeland Ø; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., Flatley C; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Copenhagen University Hospital Biobank Unit, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark., Finel M; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Zhao M; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA., Lazarus P; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Pulmonary Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Magnus P; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Andreassen OA; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Njølstad PR; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Children and Youth Clinic, Haukeland University Hospital, Bergen, Norway., Grant SFA; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Copenhagen University Hospital Biobank Unit, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark.; Department of Biology, University of Copenhagen, Copenhagen, Denmark., Muglia LJ; Office of the President, Burroughs Wellcome Fund, Research Triangle Park, NC, USA.; Division of Human Genetics, Center for the Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Johansson S; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway., Zhang G; Division of Human Genetics, Center for the Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Jacobsson B; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden. bo.jacobsson@obgyn.gu.se.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway. bo.jacobsson@obgyn.gu.se.
Source: Nature communications [Nat Commun] 2024 Aug 30; Vol. 15 (1), pp. 7550. Date of Electronic Publication: 2024 Aug 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Solé-Navais+P%22">Solé-Navais P</searchLink>; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden. pol.sole.navais@gu.se.<br /><searchLink fieldCode="AU" term="%22Juodakis+J%22">Juodakis J</searchLink>; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Ytterberg+K%22">Ytterberg K</searchLink>; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Copenhagen University Hospital Biobank Unit, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bradfield+JP%22">Bradfield JP</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Quantinuum Research LLC, Wayne, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vaudel+M%22">Vaudel M</searchLink>; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22LaBella+AL%22">LaBella AL</searchLink>; Department of Bioinformatics and Genomics, College of Computing and Informatics, North Carolina Research Campus, University of North Carolina at Charlotte, Kannapolis, NC, USA.<br /><searchLink fieldCode="AU" term="%22Helgeland+Ø%22">Helgeland Ø</searchLink>; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Flatley+C%22">Flatley C</searchLink>; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Geller+F%22">Geller F</searchLink>; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Copenhagen University Hospital Biobank Unit, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Finel+M%22">Finel M</searchLink>; Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.<br /><searchLink fieldCode="AU" term="%22Lazarus+P%22">Lazarus P</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hakonarson+H%22">Hakonarson H</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Pulmonary Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Magnus+P%22">Magnus P</searchLink>; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Njølstad+PR%22">Njølstad PR</searchLink>; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Children and Youth Clinic, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Grant+SFA%22">Grant SFA</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Feenstra+B%22">Feenstra B</searchLink>; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Copenhagen University Hospital Biobank Unit, Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark.; Department of Biology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Muglia+LJ%22">Muglia LJ</searchLink>; Office of the President, Burroughs Wellcome Fund, Research Triangle Park, NC, USA.; Division of Human Genetics, Center for the Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Johansson+S%22">Johansson S</searchLink>; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Division of Human Genetics, Center for the Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Jacobsson+B%22">Jacobsson B</searchLink>; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden. bo.jacobsson@obgyn.gu.se.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway. bo.jacobsson@obgyn.gu.se.
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