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Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.

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Title: Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
Authors: Neelsen LC; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany., Riel EB; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Rinné S; Institute of Physiology and Pathophysiology, Philipps-University of Marburg, Marburg, Germany., Schmid FR; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Jürs BC; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.; MSH Medical School Hamburg, University of Applied Sciences and Medical University, Hamburg, Germany., Bedoya M; Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca, Chile.; Laboratorio de Bioinformática y Química Computacional (LBQC), Departamento de Medicina Traslacional, Facultad de Medicina, Universidad Católica del Maule, Talca, Chile., Langer JP; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany., Eymsh B; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany., Kiper AK; Institute of Physiology and Pathophysiology, Philipps-University of Marburg, Marburg, Germany., Cordeiro S; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany., Decher N; Institute of Physiology and Pathophysiology, Philipps-University of Marburg, Marburg, Germany. decher@staff.uni-marburg.de., Baukrowitz T; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany. t.baukrowitz@physiologie.uni-kiel.de., Schewe M; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany. m.schewe@physiologie.uni-kiel.de.
Source: Nature communications [Nat Commun] 2024 Aug 30; Vol. 15 (1), pp. 7545. Date of Electronic Publication: 2024 Aug 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K<subscript>2P</subscript> channel TALK-2.
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  Data: <searchLink fieldCode="AU" term="%22Neelsen+LC%22">Neelsen LC</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Riel+EB%22">Riel EB</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rinné+S%22">Rinné S</searchLink>; Institute of Physiology and Pathophysiology, Philipps-University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+FR%22">Schmid FR</searchLink>; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Jürs+BC%22">Jürs BC</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.; MSH Medical School Hamburg, University of Applied Sciences and Medical University, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bedoya+M%22">Bedoya M</searchLink>; Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca, Chile.; Laboratorio de Bioinformática y Química Computacional (LBQC), Departamento de Medicina Traslacional, Facultad de Medicina, Universidad Católica del Maule, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Langer+JP%22">Langer JP</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Eymsh+B%22">Eymsh B</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kiper+AK%22">Kiper AK</searchLink>; Institute of Physiology and Pathophysiology, Philipps-University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cordeiro+S%22">Cordeiro S</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Decher+N%22">Decher N</searchLink>; Institute of Physiology and Pathophysiology, Philipps-University of Marburg, Marburg, Germany. decher@staff.uni-marburg.de.<br /><searchLink fieldCode="AU" term="%22Baukrowitz+T%22">Baukrowitz T</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany. t.baukrowitz@physiologie.uni-kiel.de.<br /><searchLink fieldCode="AU" term="%22Schewe+M%22">Schewe M</searchLink>; Institute of Physiology, Christian-Albrechts University of Kiel, Kiel, Germany. m.schewe@physiologie.uni-kiel.de.
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