Inhibition of falcilysin from Plasmodium falciparum by interference with its closed-to-open dynamic transition.
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| Title: | Inhibition of falcilysin from Plasmodium falciparum by interference with its closed-to-open dynamic transition. |
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| Authors: | Lin J; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., Yan X; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., Chung Z; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., Liew CW; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., El Sahili A; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., Pechnikova EV; Materials and Structural Analysis Division, Thermo Fisher Scientific, Eindhoven, Netherlands.; Dens Solutions, Informaticalaan 12, 2628 ZD, Delft, Netherlands., Preiser PR; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, 1 CREATE Way, 138602, Singapore, Singapore., Bozdech Z; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., Gao YG; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore., Lescar J; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore. julien@ntu.edu.sg.; NTU Institute of Structural Biology, Nanyang Technological University, Experimental Medicine Building (EMB), 59 Nanyang Drive, Level 06-01, 636921, Singapore, Singapore. julien@ntu.edu.sg.; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, 1 CREATE Way, 138602, Singapore, Singapore. julien@ntu.edu.sg. |
| Source: | Communications biology [Commun Biol] 2024 Aug 31; Vol. 7 (1), pp. 1070. Date of Electronic Publication: 2024 Aug 31. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2399-3642 |
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| DOI: | 10.1038/s42003-024-06774-6 |