Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.

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Title: Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
Authors: Zhu JX; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Chu F; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Zhao WM; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Shi R; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Wang ZJ; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Li XL; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Zhu YY; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China., Wang DG; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China. wangdeguang@ahmu.edu.cn.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China. wangdeguang@ahmu.edu.cn.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Feb; Vol. 398 (2), pp. 1973-1989. Date of Electronic Publication: 2024 Sep 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
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  Data: Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+JX%22">Zhu JX</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Chu+F%22">Chu F</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Zhao+WM%22">Zhao WM</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Shi+R%22">Shi R</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Wang+ZJ%22">Wang ZJ</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Li+XL%22">Li XL</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Zhu+YY%22">Zhu YY</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China.<br /><searchLink fieldCode="AU" term="%22Wang+DG%22">Wang DG</searchLink>; Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China. wangdeguang@ahmu.edu.cn.; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Affiliated Hospital of Anhui Medical University, No. 678, Furong Road, Lianhua Community, Shushan District, Hefei City, Anhui Province, China. wangdeguang@ahmu.edu.cn.
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        Value: 10.1007/s00210-024-03398-9
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        StartPage: 1973
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      – TitleFull: Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
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