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Influence of age and co-medication on dolutegravir glucuronidation in paediatric patients.

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Title: Influence of age and co-medication on dolutegravir glucuronidation in paediatric patients.
Authors: Jacobs TG; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Waalewijn H; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Houlden L; Medical Research Council Clinical Trials Unit, University College London, London, UK., Bollen PDJ; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.; Hospital Gelderse Vallei, Ede, The Netherlands., Nanduudu A; Joint Clinical Research Centre, Kampala, Uganda., Nambi E; Joint Clinical Research Centre, Kampala, Uganda., Cassim H; Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Lugemwa A; Joint Clinical Research Centre, Mbarara, Uganda., Makumbi S; Joint Clinical Research Centre, Mbarara, Uganda., Monkiewicz LN; Medical Research Council Clinical Trials Unit, University College London, London, UK., Shakeshaft C; Medical Research Council Clinical Trials Unit, University College London, London, UK., Bamford A; Medical Research Council Clinical Trials Unit, University College London, London, UK., Archary M; Durban International Clinical Research Site, Durban, South Africa., Musuro G; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe., Chidziva E; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe., Mujuru HA; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe., Bwakura-Dangarembizi M; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe., Chabala C; Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia.; Children's Hospital, University Teaching Hospitals, Lusaka, Zambia., Turkova A; Medical Research Council Clinical Trials Unit, University College London, London, UK., Gibb DM; Medical Research Council Clinical Trials Unit, University College London, London, UK., Cotton MF; Family Centre for Research with Ubuntu, Stellenbosch University, Cape Town, South Africa., Aarnoutse R; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Burger DM; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Colbers A; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Nov; Vol. 90 (11), pp. 2947-2952. Date of Electronic Publication: 2024 Sep 03.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Influence of age and co-medication on dolutegravir glucuronidation in paediatric patients.
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  Data: <searchLink fieldCode="AU" term="%22Jacobs+TG%22">Jacobs TG</searchLink>; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Waalewijn+H%22">Waalewijn H</searchLink>; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Houlden+L%22">Houlden L</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bollen+PDJ%22">Bollen PDJ</searchLink>; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.; Hospital Gelderse Vallei, Ede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nanduudu+A%22">Nanduudu A</searchLink>; Joint Clinical Research Centre, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Nambi+E%22">Nambi E</searchLink>; Joint Clinical Research Centre, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Cassim+H%22">Cassim H</searchLink>; Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Lugemwa+A%22">Lugemwa A</searchLink>; Joint Clinical Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Makumbi+S%22">Makumbi S</searchLink>; Joint Clinical Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Monkiewicz+LN%22">Monkiewicz LN</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shakeshaft+C%22">Shakeshaft C</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bamford+A%22">Bamford A</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Archary+M%22">Archary M</searchLink>; Durban International Clinical Research Site, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Musuro+G%22">Musuro G</searchLink>; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Chidziva+E%22">Chidziva E</searchLink>; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Mujuru+HA%22">Mujuru HA</searchLink>; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Bwakura-Dangarembizi+M%22">Bwakura-Dangarembizi M</searchLink>; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Chabala+C%22">Chabala C</searchLink>; Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia.; Children's Hospital, University Teaching Hospitals, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Turkova+A%22">Turkova A</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gibb+DM%22">Gibb DM</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cotton+MF%22">Cotton MF</searchLink>; Family Centre for Research with Ubuntu, Stellenbosch University, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Aarnoutse+R%22">Aarnoutse R</searchLink>; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+DM%22">Burger DM</searchLink>; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Colbers+A%22">Colbers A</searchLink>; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.
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