Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations.

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Title: Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations.
Authors: Xu W; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Hong YS; Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University School of Medicine, Baltimore, Md., Hu B; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Comhair SAA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Janocha AJ; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Zein JG; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz., Chen R; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Meyers DA; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz., Mauger DT; Department of Public Health Sciences, Pennsylvania State University School of Medicine, Hershey, Pa., Ortega VE; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz., Bleecker ER; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz., Castro M; Department of Medicine, University of Kansas School of Medicine, Kansas City, Kan., Denlinger LC; Division of Allergy, Pulmonary and Critical Care Medicine, University of Wisconsin, Madison, Wis., Fahy JV; Department of Medicine, San Francisco School of Medicine, University of California, San Francisco, Calif., Israel E; Department of Medicine, Harvard Medical School, Boston, Mass., Levy BD; Department of Medicine, Harvard Medical School, Boston, Mass., Jarjour NN; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis., Moore WC; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC., Wenzel SE; Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh School of Medicine, Pittsburgh, Pa., Gaston B; Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Ind., Liu C; Department of Biostatistics, School of Public Health, Boston University, Boston, Mass., Arking DE; Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University School of Medicine, Baltimore, Md., Erzurum SC; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio; Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: erzurus@ccf.org.
Corporate Authors: National Heart, Lung, and Blood Institute (NHLBI) Severe Asthma Research Program and TOPMed mtDNA Working Group in NHLBI Trans-omics for Precision Medicine (TOPMed) Consortium
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2025 Apr; Vol. 155 (4), pp. 1224-1235. Date of Electronic Publication: 2024 Sep 03.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Xu+W%22">Xu W</searchLink>; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Hong+YS%22">Hong YS</searchLink>; Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University School of Medicine, Baltimore, Md.<br /><searchLink fieldCode="AU" term="%22Hu+B%22">Hu B</searchLink>; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Comhair+SAA%22">Comhair SAA</searchLink>; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Janocha+AJ%22">Janocha AJ</searchLink>; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Zein+JG%22">Zein JG</searchLink>; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Meyers+DA%22">Meyers DA</searchLink>; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz.<br /><searchLink fieldCode="AU" term="%22Mauger+DT%22">Mauger DT</searchLink>; Department of Public Health Sciences, Pennsylvania State University School of Medicine, Hershey, Pa.<br /><searchLink fieldCode="AU" term="%22Ortega+VE%22">Ortega VE</searchLink>; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz.<br /><searchLink fieldCode="AU" term="%22Bleecker+ER%22">Bleecker ER</searchLink>; Department of Internal Medicine, Division of Respiratory Medicine, Mayo Clinic, Scottsdale, Ariz.<br /><searchLink fieldCode="AU" term="%22Castro+M%22">Castro M</searchLink>; Department of Medicine, University of Kansas School of Medicine, Kansas City, Kan.<br /><searchLink fieldCode="AU" term="%22Denlinger+LC%22">Denlinger LC</searchLink>; Division of Allergy, Pulmonary and Critical Care Medicine, University of Wisconsin, Madison, Wis.<br /><searchLink fieldCode="AU" term="%22Fahy+JV%22">Fahy JV</searchLink>; Department of Medicine, San Francisco School of Medicine, University of California, San Francisco, Calif.<br /><searchLink fieldCode="AU" term="%22Israel+E%22">Israel E</searchLink>; Department of Medicine, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Levy+BD%22">Levy BD</searchLink>; Department of Medicine, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Jarjour+NN%22">Jarjour NN</searchLink>; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.<br /><searchLink fieldCode="AU" term="%22Moore+WC%22">Moore WC</searchLink>; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC.<br /><searchLink fieldCode="AU" term="%22Wenzel+SE%22">Wenzel SE</searchLink>; Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh School of Medicine, Pittsburgh, Pa.<br /><searchLink fieldCode="AU" term="%22Gaston+B%22">Gaston B</searchLink>; Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Ind.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Biostatistics, School of Public Health, Boston University, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Arking+DE%22">Arking DE</searchLink>; Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University School of Medicine, Baltimore, Md.<br /><searchLink fieldCode="AU" term="%22Erzurum+SC%22">Erzurum SC</searchLink>; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio; Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: erzurus@ccf.org.
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  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2025 Apr; Vol. 155 (4), pp. 1224-1235. <i>Date of Electronic Publication: </i>2024 Sep 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1275002 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200916749%22">00916749 </searchLink><i>NLM ISO Abbreviation: </i>J Allergy Clin Immunol <i>Subsets: </i>MEDLINE
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