Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage.
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| Title: | Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage. |
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| Authors: | Burkhalter MD; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Stiff T; Genome Damage and Stability Centre, University of Sussex, Brighton, BN1 9RQ, UK., Maerz LD; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany., Casar Tena T; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany., Wiese H; Core Unit Mass Spectrometry and Proteomics, Medical Faculty, Ulm University, 89081, Ulm, Germany., Gerhards J; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Sailer SA; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Vu LAT; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Duong Phu M; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Donow C; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany., Alupei M; Department of Dermatology, Ulm University, 89081, Ulm, Germany., Iben S; Department of Dermatology, Ulm University, 89081, Ulm, Germany., Groth M; Core Facility Next Generation Sequencing, Leibniz Institute on Aging-Fritz Lipmann Institute, 07745, Jena, Germany., Wiese S; Core Unit Mass Spectrometry and Proteomics, Medical Faculty, Ulm University, 89081, Ulm, Germany., Church JA; Department of Pediatrics, Keck School of Medicine of University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, 90033, USA., Jeggo PA; Genome Damage and Stability Centre, University of Sussex, Brighton, BN1 9RQ, UK., Philipp M; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany. melanie.philipp@uni-tuebingen.de. |
| Source: | Cell death & disease [Cell Death Dis] 2024 Sep 09; Vol. 15 (9), pp. 660. Date of Electronic Publication: 2024 Sep 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-024-07042-5 |
