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Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage.

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Title: Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage.
Authors: Burkhalter MD; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Stiff T; Genome Damage and Stability Centre, University of Sussex, Brighton, BN1 9RQ, UK., Maerz LD; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany., Casar Tena T; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany., Wiese H; Core Unit Mass Spectrometry and Proteomics, Medical Faculty, Ulm University, 89081, Ulm, Germany., Gerhards J; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Sailer SA; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Vu LAT; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Duong Phu M; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany., Donow C; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany., Alupei M; Department of Dermatology, Ulm University, 89081, Ulm, Germany., Iben S; Department of Dermatology, Ulm University, 89081, Ulm, Germany., Groth M; Core Facility Next Generation Sequencing, Leibniz Institute on Aging-Fritz Lipmann Institute, 07745, Jena, Germany., Wiese S; Core Unit Mass Spectrometry and Proteomics, Medical Faculty, Ulm University, 89081, Ulm, Germany., Church JA; Department of Pediatrics, Keck School of Medicine of University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, 90033, USA., Jeggo PA; Genome Damage and Stability Centre, University of Sussex, Brighton, BN1 9RQ, UK., Philipp M; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany. melanie.philipp@uni-tuebingen.de.
Source: Cell death & disease [Cell Death Dis] 2024 Sep 09; Vol. 15 (9), pp. 660. Date of Electronic Publication: 2024 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage.
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  Data: <searchLink fieldCode="AU" term="%22Burkhalter+MD%22">Burkhalter MD</searchLink>; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Stiff+T%22">Stiff T</searchLink>; Genome Damage and Stability Centre, University of Sussex, Brighton, BN1 9RQ, UK.<br /><searchLink fieldCode="AU" term="%22Maerz+LD%22">Maerz LD</searchLink>; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Casar+Tena+T%22">Casar Tena T</searchLink>; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Wiese+H%22">Wiese H</searchLink>; Core Unit Mass Spectrometry and Proteomics, Medical Faculty, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Gerhards+J%22">Gerhards J</searchLink>; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Sailer+SA%22">Sailer SA</searchLink>; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Vu+LAT%22">Vu LAT</searchLink>; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Duong+Phu+M%22">Duong Phu M</searchLink>; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Donow+C%22">Donow C</searchLink>; Institute for Biochemistry and Molecular Biology, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Alupei+M%22">Alupei M</searchLink>; Department of Dermatology, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Iben+S%22">Iben S</searchLink>; Department of Dermatology, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Groth+M%22">Groth M</searchLink>; Core Facility Next Generation Sequencing, Leibniz Institute on Aging-Fritz Lipmann Institute, 07745, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Wiese+S%22">Wiese S</searchLink>; Core Unit Mass Spectrometry and Proteomics, Medical Faculty, Ulm University, 89081, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Church+JA%22">Church JA</searchLink>; Department of Pediatrics, Keck School of Medicine of University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, 90033, USA.<br /><searchLink fieldCode="AU" term="%22Jeggo+PA%22">Jeggo PA</searchLink>; Genome Damage and Stability Centre, University of Sussex, Brighton, BN1 9RQ, UK.<br /><searchLink fieldCode="AU" term="%22Philipp+M%22">Philipp M</searchLink>; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, 72074, Tübingen, Germany. melanie.philipp@uni-tuebingen.de.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2024 Sep 09; Vol. 15 (9), pp. 660. <i>Date of Electronic Publication: </i>2024 Sep 09.
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