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CD71 expressing circulating neutrophils serve as a novel prognostic biomarker for metastatic spread and reduced outcome in pancreatic ductal adenocarcinoma patients.

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Title: CD71 expressing circulating neutrophils serve as a novel prognostic biomarker for metastatic spread and reduced outcome in pancreatic ductal adenocarcinoma patients.
Authors: Hansen FJ; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Mittelstädt A; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Clausen FN; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Knoedler S; Institute of Regenerative Biology and Medicine, Helmholtz Center Munich, Ingolstädter Landtsraße 1, 85764, Neuherberg, Germany., Knoedler L; Division of Genetic Immunotherapy (LIT), University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany., Klöckner S; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Kuchenreuther I; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Mazurie J; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Arnold LS; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Anthuber A; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Jacobsen A; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Merkel S; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Weisel N; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Klösch B; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Karabiber A; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Tacyildiz I; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Czubayko F; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Reitberger H; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Gendy AE; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Brunner M; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany., Krautz C; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany., Wolff K; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.; First Department of Medicine, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Mihai S; Zentrallabor im Universitätsklinikum, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Krankenhausstr. 12, Erlangen, Germany., Neufert C; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.; First Department of Medicine, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Siebler J; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.; First Department of Medicine, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Grützmann R; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany., Weber GF; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany. Georg.Weber@uk-erlangen.de.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany. Georg.Weber@uk-erlangen.de.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany. Georg.Weber@uk-erlangen.de., David P; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.
Source: Scientific reports [Sci Rep] 2024 Sep 10; Vol. 14 (1), pp. 21164. Date of Electronic Publication: 2024 Sep 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CD71 expressing circulating neutrophils serve as a novel prognostic biomarker for metastatic spread and reduced outcome in pancreatic ductal adenocarcinoma patients.
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  Data: <searchLink fieldCode="AU" term="%22Hansen+FJ%22">Hansen FJ</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Mittelstädt+A%22">Mittelstädt A</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Clausen+FN%22">Clausen FN</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Knoedler+S%22">Knoedler S</searchLink>; Institute of Regenerative Biology and Medicine, Helmholtz Center Munich, Ingolstädter Landtsraße 1, 85764, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Knoedler+L%22">Knoedler L</searchLink>; Division of Genetic Immunotherapy (LIT), University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Klöckner+S%22">Klöckner S</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Kuchenreuther+I%22">Kuchenreuther I</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Mazurie+J%22">Mazurie J</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Arnold+LS%22">Arnold LS</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Anthuber+A%22">Anthuber A</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Jacobsen+A%22">Jacobsen A</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Merkel+S%22">Merkel S</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Weisel+N%22">Weisel N</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Klösch+B%22">Klösch B</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Karabiber+A%22">Karabiber A</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Tacyildiz+I%22">Tacyildiz I</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Czubayko+F%22">Czubayko F</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Reitberger+H%22">Reitberger H</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Gendy+AE%22">Gendy AE</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Brunner+M%22">Brunner M</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Krautz+C%22">Krautz C</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Wolff+K%22">Wolff K</searchLink>; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.; First Department of Medicine, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Mihai+S%22">Mihai S</searchLink>; Zentrallabor im Universitätsklinikum, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Krankenhausstr. 12, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Neufert+C%22">Neufert C</searchLink>; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.; First Department of Medicine, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Siebler+J%22">Siebler J</searchLink>; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.; First Department of Medicine, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Grützmann+R%22">Grützmann R</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+GF%22">Weber GF</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany. Georg.Weber@uk-erlangen.de.; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany. Georg.Weber@uk-erlangen.de.; Bavarian Cancer Research Center (BZKF), Erlangen, Germany. Georg.Weber@uk-erlangen.de.<br /><searchLink fieldCode="AU" term="%22David+P%22">David P</searchLink>; Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054, Erlangen, Germany.
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