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An open-source framework for end-to-end analysis of electronic health record data.

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Title: An open-source framework for end-to-end analysis of electronic health record data.
Authors: Heumos L; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Ehmele P; Institute of Computational Biology, Helmholtz Munich, Munich, Germany., Treis T; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Upmeier Zu Belzen J; Health Data Science Unit, Heidelberg University and BioQuant, Heidelberg, Germany., Roellin E; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., May L; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., Namsaraeva A; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Konrad Zuse School of Excellence in Learning and Intelligent Systems (ELIZA), Darmstadt, Germany., Horlava N; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Shitov VA; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Zhang X; Institute of Computational Biology, Helmholtz Munich, Munich, Germany., Zappia L; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., Knoll R; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany., Lang NJ; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany., Hetzel L; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., Virshup I; Institute of Computational Biology, Helmholtz Munich, Munich, Germany., Sikkema L; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Curion F; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., Eils R; Health Data Science Unit, Heidelberg University and BioQuant, Heidelberg, Germany.; Center for Digital Health, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany., Schiller HB; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.; Research Unit, Precision Regenerative Medicine (PRM), Helmholtz Munich, Munich, Germany., Hilgendorff A; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.; Center for Comprehensive Developmental Care (CDeCLMU) at the Social Pediatric Center, Dr. von Hauner Children's Hospital, LMU Hospital, Ludwig Maximilian University, Munich, Germany., Theis FJ; Institute of Computational Biology, Helmholtz Munich, Munich, Germany. fabian.theis@helmholtz-muenchen.de.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-muenchen.de.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-muenchen.de.
Source: Nature medicine [Nat Med] 2024 Nov; Vol. 30 (11), pp. 3369-3380. Date of Electronic Publication: 2024 Sep 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Heumos+L%22">Heumos L</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ehmele+P%22">Ehmele P</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Treis+T%22">Treis T</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Upmeier+Zu+Belzen+J%22">Upmeier Zu Belzen J</searchLink>; Health Data Science Unit, Heidelberg University and BioQuant, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Roellin+E%22">Roellin E</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22May+L%22">May L</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Namsaraeva+A%22">Namsaraeva A</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Konrad Zuse School of Excellence in Learning and Intelligent Systems (ELIZA), Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Horlava+N%22">Horlava N</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Shitov+VA%22">Shitov VA</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zappia+L%22">Zappia L</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Knoll+R%22">Knoll R</searchLink>; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Lang+NJ%22">Lang NJ</searchLink>; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hetzel+L%22">Hetzel L</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Virshup+I%22">Virshup I</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sikkema+L%22">Sikkema L</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Curion+F%22">Curion F</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Eils+R%22">Eils R</searchLink>; Health Data Science Unit, Heidelberg University and BioQuant, Heidelberg, Germany.; Center for Digital Health, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schiller+HB%22">Schiller HB</searchLink>; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.; Research Unit, Precision Regenerative Medicine (PRM), Helmholtz Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hilgendorff+A%22">Hilgendorff A</searchLink>; Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M bioArchive; Helmholtz Zentrum Munich; member of the German Center for Lung Research (DZL), Munich, Germany.; Center for Comprehensive Developmental Care (CDeCLMU) at the Social Pediatric Center, Dr. von Hauner Children's Hospital, LMU Hospital, Ludwig Maximilian University, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Theis+FJ%22">Theis FJ</searchLink>; Institute of Computational Biology, Helmholtz Munich, Munich, Germany. fabian.theis@helmholtz-muenchen.de.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-muenchen.de.; Department of Mathematics, School of Computation, Information and Technology, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-muenchen.de.
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