Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy.

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Title: Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy.
Authors: DeForest N; Division of Endocrinology, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Wang Y; Division of Endocrinology, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Zhu Z; Division of Endocrinology, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Dron JS; Center for Genomic Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Programs in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Koesterer R; Programs in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Natarajan P; Center for Genomic Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Flannick J; Programs in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Amariuta T; Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, CA, USA.; Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Majithia AR; Division of Endocrinology, Department of Medicine, University of California San Diego, La Jolla, CA, USA. amajithia@health.ucsd.edu.
Source: Nature communications [Nat Commun] 2024 Sep 14; Vol. 15 (1), pp. 8068. Date of Electronic Publication: 2024 Sep 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-024-52105-y