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Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.

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Title: Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.
Authors: Tran MT; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Grosse S; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Carbajo RJ; Janssen Research and Development, Janssen-Cilag, S.A., C/Jarama 75, 45007 Toledo, Spain., Jacoby E; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Yin Y; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, Pennsylvania 19477, United States., Yu X; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, Pennsylvania 19477, United States., Martinez C; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Stoops B; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Cooymans L; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Hu L; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Lutter FH; Chemical Process R&D, Discovery Process Research, Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Pieters S; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Tan E; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Alcázar J; Janssen Research and Development, Janssen-Cilag, S.A., C/Jarama 75, 45007 Toledo, Spain., Roymans D; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., van Vlijmen H; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Rigaux P; Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Sharma S; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, Pennsylvania 19477, United States., Jonckers THM; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Aug 02; Vol. 15 (9), pp. 1549-1558. Date of Electronic Publication: 2024 Aug 02 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
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  Data: Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Tran+MT%22">Tran MT</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Grosse+S%22">Grosse S</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Carbajo+RJ%22">Carbajo RJ</searchLink>; Janssen Research and Development, Janssen-Cilag, S.A., C/Jarama 75, 45007 Toledo, Spain.<br /><searchLink fieldCode="AU" term="%22Jacoby+E%22">Jacoby E</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Yin+Y%22">Yin Y</searchLink>; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, Pennsylvania 19477, United States.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, Pennsylvania 19477, United States.<br /><searchLink fieldCode="AU" term="%22Martinez+C%22">Martinez C</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Stoops+B%22">Stoops B</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Cooymans+L%22">Cooymans L</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Hu+L%22">Hu L</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Lutter+FH%22">Lutter FH</searchLink>; Chemical Process R&D, Discovery Process Research, Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Pieters+S%22">Pieters S</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Tan+E%22">Tan E</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Alcázar+J%22">Alcázar J</searchLink>; Janssen Research and Development, Janssen-Cilag, S.A., C/Jarama 75, 45007 Toledo, Spain.<br /><searchLink fieldCode="AU" term="%22Roymans+D%22">Roymans D</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22van+Vlijmen+H%22">van Vlijmen H</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Rigaux+P%22">Rigaux P</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Sharma+S%22">Sharma S</searchLink>; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, Pennsylvania 19477, United States.<br /><searchLink fieldCode="AU" term="%22Jonckers+THM%22">Jonckers THM</searchLink>; Janssen Pharmaceutica NV, 2340 Beerse, Belgium.
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  Data: <searchLink fieldCode="JN" term="%22101521073%22">ACS medicinal chemistry letters</searchLink> [ACS Med Chem Lett] 2024 Aug 02; Vol. 15 (9), pp. 1549-1558. <i>Date of Electronic Publication: </i>2024 Aug 02 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101521073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1948-5875 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219485875%22">19485875 </searchLink><i>NLM ISO Abbreviation: </i>ACS Med Chem Lett <i>Subsets: </i>PubMed not MEDLINE
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