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A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination.

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Title: A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination.
Authors: Bai Q; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Shao E; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Tsinghua University School of Medicine, Beijing, China., Ma D; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Jiao B; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Tsinghua University School of Medicine, Beijing, China., Scheetz SD; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Hartnett-Scott KA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Ilin VA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Aizenman E; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Kofler J; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Burton EA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA. eab25@pitt.edu.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA. eab25@pitt.edu.; Geriatrics Research, Education and Clinical Center, Pittsburgh VA Healthcare System, Pittsburgh, PA, 15240, USA. eab25@pitt.edu.
Source: Nature communications [Nat Commun] 2024 Sep 18; Vol. 15 (1), pp. 8195. Date of Electronic Publication: 2024 Sep 18.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination.
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  Data: <searchLink fieldCode="AU" term="%22Bai+Q%22">Bai Q</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Shao+E%22">Shao E</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Tsinghua University School of Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+D%22">Ma D</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Jiao+B%22">Jiao B</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Tsinghua University School of Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Scheetz+SD%22">Scheetz SD</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Hartnett-Scott+KA%22">Hartnett-Scott KA</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Ilin+VA%22">Ilin VA</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Aizenman+E%22">Aizenman E</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kofler+J%22">Kofler J</searchLink>; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Burton+EA%22">Burton EA</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA. eab25@pitt.edu.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA. eab25@pitt.edu.; Geriatrics Research, Education and Clinical Center, Pittsburgh VA Healthcare System, Pittsburgh, PA, 15240, USA. eab25@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Sep 18; Vol. 15 (1), pp. 8195. <i>Date of Electronic Publication: </i>2024 Sep 18.
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