A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination.
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| Title: | A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination. |
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| Authors: | Bai Q; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Shao E; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Tsinghua University School of Medicine, Beijing, China., Ma D; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Jiao B; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Tsinghua University School of Medicine, Beijing, China., Scheetz SD; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Hartnett-Scott KA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Ilin VA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Aizenman E; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Kofler J; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Burton EA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, 15213, USA. eab25@pitt.edu.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, 15213, USA. eab25@pitt.edu.; Geriatrics Research, Education and Clinical Center, Pittsburgh VA Healthcare System, Pittsburgh, PA, 15240, USA. eab25@pitt.edu. |
| Source: | Nature communications [Nat Commun] 2024 Sep 18; Vol. 15 (1), pp. 8195. Date of Electronic Publication: 2024 Sep 18. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-52173-0 |
