Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway.

Saved in:
Bibliographic Details
Title: Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway.
Authors: Xu W; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Endocrinology, The First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang 310003, China., Zhang D; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Ma Y; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Endocrinology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu 225009, China., Gaspar RC; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Kahn M; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Nasiri A; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA., Murray S; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA., Samuel VT; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; VA Connecticut Healthcare System, West Haven, CT 06516, USA. Electronic address: varman.samuel@yale.edu., Shulman GI; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: gerald.shulman@yale.edu.
Source: Cell reports [Cell Rep] 2024 Oct 22; Vol. 43 (10), pp. 114746. Date of Electronic Publication: 2024 Sep 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2024.114746