Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation.

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Title: Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation.
Authors: Heintzman DR; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Sinard RC; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Fisher EL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Ye X; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Patterson AR; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Elasy JH; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Voss K; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Chi C; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Sugiura A; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Rodriguez-Garcia GJ; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Chowdhury NU; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Arner EN; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Krystoviak ES; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.; Cell Imaging Shared Resource, Vanderbilt University, Nashville, TN, USA., Mason FM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Toudji YT; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Steiner KK; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Khan W; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Olson LM; Vanderbilt Technologies for Advanced Genomics (VANTAGE), Vanderbilt University Medical Center, Nashville, TN, USA., Jones AL; Vanderbilt Technologies for Advanced Genomics (VANTAGE), Vanderbilt University Medical Center, Nashville, TN, USA., Hong HS; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Bass L; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Beier KL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Deng W; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Lyssiotis CA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Newcomb DC; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA., Bick AG; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Rathmell WK; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Wilson JT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Rathmell JC; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
Source: Science immunology [Sci Immunol] 2024 Sep 20; Vol. 9 (99), pp. eadp3475. Date of Electronic Publication: 2024 Sep 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
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  Data: Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Heintzman+DR%22">Heintzman DR</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Sinard+RC%22">Sinard RC</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Fisher+EL%22">Fisher EL</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ye+X%22">Ye X</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+AR%22">Patterson AR</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Elasy+JH%22">Elasy JH</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Voss+K%22">Voss K</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chi+C%22">Chi C</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Sugiura+A%22">Sugiura A</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Garcia+GJ%22">Rodriguez-Garcia GJ</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chowdhury+NU%22">Chowdhury NU</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Arner+EN%22">Arner EN</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Krystoviak+ES%22">Krystoviak ES</searchLink>; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.; Cell Imaging Shared Resource, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Mason+FM%22">Mason FM</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Toudji+YT%22">Toudji YT</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Steiner+KK%22">Steiner KK</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Khan+W%22">Khan W</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Olson+LM%22">Olson LM</searchLink>; Vanderbilt Technologies for Advanced Genomics (VANTAGE), Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Jones+AL%22">Jones AL</searchLink>; Vanderbilt Technologies for Advanced Genomics (VANTAGE), Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Hong+HS%22">Hong HS</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Bass+L%22">Bass L</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Beier+KL%22">Beier KL</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Deng+W%22">Deng W</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Lyssiotis+CA%22">Lyssiotis CA</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Newcomb+DC%22">Newcomb DC</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Bick+AG%22">Bick AG</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Rathmell+WK%22">Rathmell WK</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+JT%22">Wilson JT</searchLink>; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Rathmell+JC%22">Rathmell JC</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
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  Data: <searchLink fieldCode="JN" term="%22101688624%22">Science immunology</searchLink> [Sci Immunol] 2024 Sep 20; Vol. 9 (99), pp. eadp3475. <i>Date of Electronic Publication: </i>2024 Sep 20.
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