Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors.
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| Title: | Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors. |
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| Authors: | Tsimberidou AM; Department of Investigational Cancer Therapeutics, Katherine Russell Dixie Distinguished Endowed Professor, The University of Texas MD Anderson Cancer Center, Unit 455, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. atsimber@mdanderson.org., Grothey A; Gastrointestinal Cancer Research at West Cancer Center and Research Institute, Germantown, TN, USA., Sigal D; Scripps Clinic and Scripps Cancer Center, La Jolla, CA, USA., Lenz HJ; Keck School of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA., Hochster HS; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Chao Y; Taipei Veterans General Hospital, Taipei, Taiwan., Bai LY; China Medical University Hospital, Taichung City, Taiwan., Yen CL; National Cheng Kung University Hospital, Tainan, Taiwan., Xu D; OBI Pharma USA, Inc, San Diego, CA, USA., Saville MW; OBI Pharma USA, Inc, San Diego, CA, USA. |
| Source: | Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 Dec; Vol. 94 (6), pp. 787-798. Date of Electronic Publication: 2024 Sep 23. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II; Multicenter Study |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39311947 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tsimberidou+AM%22">Tsimberidou AM</searchLink>; Department of Investigational Cancer Therapeutics, Katherine Russell Dixie Distinguished Endowed Professor, The University of Texas MD Anderson Cancer Center, Unit 455, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. atsimber@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Grothey+A%22">Grothey A</searchLink>; Gastrointestinal Cancer Research at West Cancer Center and Research Institute, Germantown, TN, USA.<br /><searchLink fieldCode="AU" term="%22Sigal+D%22">Sigal D</searchLink>; Scripps Clinic and Scripps Cancer Center, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lenz+HJ%22">Lenz HJ</searchLink>; Keck School of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hochster+HS%22">Hochster HS</searchLink>; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Chao+Y%22">Chao Y</searchLink>; Taipei Veterans General Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Bai+LY%22">Bai LY</searchLink>; China Medical University Hospital, Taichung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yen+CL%22">Yen CL</searchLink>; National Cheng Kung University Hospital, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Xu+D%22">Xu D</searchLink>; OBI Pharma USA, Inc, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Saville+MW%22">Saville MW</searchLink>; OBI Pharma USA, Inc, San Diego, CA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227806519%22">Cancer chemotherapy and pharmacology</searchLink> [Cancer Chemother Pharmacol] 2024 Dec; Vol. 94 (6), pp. 787-798. <i>Date of Electronic Publication: </i>2024 Sep 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>7806519 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0843 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203445704%22">03445704 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Chemother Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39311947 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00280-024-04714-z Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 787 Titles: – TitleFull: Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tsimberidou AM – PersonEntity: Name: NameFull: Grothey A – PersonEntity: Name: NameFull: Sigal D – PersonEntity: Name: NameFull: Lenz HJ – PersonEntity: Name: NameFull: Hochster HS – PersonEntity: Name: NameFull: Chao Y – PersonEntity: Name: NameFull: Bai LY – PersonEntity: Name: NameFull: Yen CL – PersonEntity: Name: NameFull: Xu D – PersonEntity: Name: NameFull: Saville MW IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2024 Dec Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1432-0843 Numbering: – Type: volume Value: 94 – Type: issue Value: 6 Titles: – TitleFull: Cancer chemotherapy and pharmacology Type: main |
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