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GDF15 antagonism limits severe heart failure and prevents cardiac cachexia.

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Title: GDF15 antagonism limits severe heart failure and prevents cardiac cachexia.
Authors: Takaoka M; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK., Tadross JA; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK.; Department of Histopathology, East Midlands & East of England Genomic Laboratory, Cambridge, UK., Al-Hadithi ABAK; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK., Zhao X; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK., Villena-Gutiérrez R; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Tromp J; University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.; Saw Swee Hock School of Public Health, National University of Singapore & the National University Health System, Singapore., Absar S; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK., Au M; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK., Harrison J; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK., Coll AP; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK., Marciniak SJ; Cambridge Institute for Medical Research, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Rimmington D; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK., Oliver E; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigaciones Biomédicas en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Centro de Investigaciones Biologicas Margarita Salas (CIB-CSIC), Madrid, Spain., Ibáñez B; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigaciones Biomédicas en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; IIS-Hospital Fundacion Jimenez Diaz, Madrid, Spain., Voors AA; University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., O'Rahilly S; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK., Mallat Z; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.; Paris Cardiovascular Research Center, Université Paris Cité, INSERM UMRS 970, Paris, France., Goodall JC; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.
Source: Cardiovascular research [Cardiovasc Res] 2024 Dec 31; Vol. 120 (17), pp. 2249-2260.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GDF15 antagonism limits severe heart failure and prevents cardiac cachexia.
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  Data: <searchLink fieldCode="AU" term="%22Takaoka+M%22">Takaoka M</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Tadross+JA%22">Tadross JA</searchLink>; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK.; Department of Histopathology, East Midlands & East of England Genomic Laboratory, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Al-Hadithi+ABAK%22">Al-Hadithi ABAK</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Villena-Gutiérrez+R%22">Villena-Gutiérrez R</searchLink>; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tromp+J%22">Tromp J</searchLink>; University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.; Saw Swee Hock School of Public Health, National University of Singapore & the National University Health System, Singapore.<br /><searchLink fieldCode="AU" term="%22Absar+S%22">Absar S</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Au+M%22">Au M</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Harrison+J%22">Harrison J</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Coll+AP%22">Coll AP</searchLink>; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Marciniak+SJ%22">Marciniak SJ</searchLink>; Cambridge Institute for Medical Research, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Rimmington+D%22">Rimmington D</searchLink>; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Oliver+E%22">Oliver E</searchLink>; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigaciones Biomédicas en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Centro de Investigaciones Biologicas Margarita Salas (CIB-CSIC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ibáñez+B%22">Ibáñez B</searchLink>; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigaciones Biomédicas en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; IIS-Hospital Fundacion Jimenez Diaz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Voors+AA%22">Voors AA</searchLink>; University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22O'Rahilly+S%22">O'Rahilly S</searchLink>; Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science and Medical Research Council, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Mallat+Z%22">Mallat Z</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.; Paris Cardiovascular Research Center, Université Paris Cité, INSERM UMRS 970, Paris, France.<br /><searchLink fieldCode="AU" term="%22Goodall+JC%22">Goodall JC</searchLink>; Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge CB2 0QQ, UK.
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  Data: <searchLink fieldCode="JN" term="%220077427%22">Cardiovascular research</searchLink> [Cardiovasc Res] 2024 Dec 31; Vol. 120 (17), pp. 2249-2260.
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              Text: 2024 Dec 31
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