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Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells.

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Title: Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells.
Authors: Staudt S; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Nikolka F; Department of Bioinformatics and Biochemistry, Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany., Perl M; University Hospital Regensburg, Department of Internal Medicine III, Hematology & Internal Oncology, Regensburg, Germany., Franz J; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Leblay N; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Yuan XK; Precision Oncology Hub, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Larrayoz M; Hemato-Oncology Program, Cima Universidad de Navarra, Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Cancer Center Clinica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Lozano T; Program of Immunology and Immunotherapy, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain., Warmuth L; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany., Fante MA; University Hospital Regensburg, Department of Internal Medicine III, Hematology & Internal Oncology, Regensburg, Germany., Skorpskaite A; Life Sciences Center - European Molecular Biology Laboratory (LSC-EMBL) Partnership for Genome Editing Technologies, Vilnius University - Life Sciences Center, Vilnius University, Vilnius, Lithuania., Fei T; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Bromberg M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., San Martin-Uriz P; Hemato-Oncology Program, Cima Universidad de Navarra, Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Cancer Center Clinica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Rodriguez-Madoz JR; Hemato-Oncology Program, Cima Universidad de Navarra, Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Cancer Center Clinica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Ziegler-Martin K; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Adil-Gholam N; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Benz P; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Tran Huu P; Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Vienna, Austria., Freitag F; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Riester Z; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.; Mildred Scheel Early Career Center, University Hospital of Würzburg, Würzburg, Germany., Stein-Thoeringer C; Innere Medizin I, Universitätsklinikum Tübingen & M3 Research Center, Universitätsklinikum Tübingen., Schmitt M; Department of Hematology, Oncology and Rheumatology, University Clinic Heidelberg, Heidelberg, Germany., Kleigrewe K; Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich, Freising, Germany., Weber J; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Mangold K; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany., Ho P; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany., Einsele H; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.; National Center for Tumor Therapy (NCT WERA), Würzburg, Germany., Prosper F; Hematology and Cell Therapy Department, Clinica Universidad de Navarra (CUN), Hemato-Oncology Program, Cima Universidad de Navarra. Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Cancer Center Clinica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Ellmeier W; Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Vienna, Austria., Busch D; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany., Visekruna A; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany., Slingerland J; City of Hope Comprehensive Cancer Center, Duarte, CA., Shouval R; Adult Bone Marrow Transplantation Service and Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Hiller K; Department of Bioinformatics and Biochemistry, Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany., Lasarte JJ; Program of Immunology and Immunotherapy, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain., Martinez-Climent JA; Hemato-Oncology Program, Cima Universidad de Navarra, Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Cancer Center Clinica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Pausch P; Life Sciences Center - European Molecular Biology Laboratory (LSC-EMBL) Partnership for Genome Editing Technologies, Vilnius University - Life Sciences Center, Vilnius University, Vilnius, Lithuania., Neri P; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., van den Brink M; City of Hope Comprehensive Cancer Center, Duarte, CA., Poeck H; University Hospital Regensburg, Department of Internal Medicine III, Hematology & Internal Oncology, Regensburg, Germany.; Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany.; Bavarian Cancer Research Center (BZKF), Regensburg & Würzburg, Germany., Hudecek M; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.; National Center for Tumor Therapy (NCT WERA), Würzburg, Germany.; Bavarian Cancer Research Center (BZKF), Regensburg & Würzburg, Germany., Luu M; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.; National Center for Tumor Therapy (NCT WERA), Würzburg, Germany.; Bavarian Cancer Research Center (BZKF), Regensburg & Würzburg, Germany.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 04. Date of Electronic Publication: 2025 Feb 04.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells.
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  Data: <searchLink fieldCode="AU" term="%22Staudt+S%22">Staudt S</searchLink>; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nikolka+F%22">Nikolka F</searchLink>; Department of Bioinformatics and Biochemistry, Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany.<br /><searchLink fieldCode="AU" term="%22Perl+M%22">Perl M</searchLink>; University Hospital Regensburg, Department of Internal Medicine III, Hematology & Internal Oncology, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Franz+J%22">Franz J</searchLink>; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Leblay+N%22">Leblay N</searchLink>; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Yuan+XK%22">Yuan XK</searchLink>; Precision Oncology Hub, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Larrayoz+M%22">Larrayoz M</searchLink>; Hemato-Oncology Program, Cima Universidad de Navarra, Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Cancer Center Clinica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Lozano+T%22">Lozano T</searchLink>; Program of Immunology and Immunotherapy, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Warmuth+L%22">Warmuth L</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fante+MA%22">Fante MA</searchLink>; University Hospital Regensburg, Department of Internal Medicine III, Hematology & Internal Oncology, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Skorpskaite+A%22">Skorpskaite A</searchLink>; 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Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.; Mildred Scheel Early Career Center, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stein-Thoeringer+C%22">Stein-Thoeringer C</searchLink>; Innere Medizin I, Universitätsklinikum Tübingen & M3 Research Center, Universitätsklinikum Tübingen.<br /><searchLink fieldCode="AU" term="%22Schmitt+M%22">Schmitt M</searchLink>; Department of Hematology, Oncology and Rheumatology, University Clinic Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kleigrewe+K%22">Kleigrewe K</searchLink>; Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich, Freising, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+J%22">Weber J</searchLink>; Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mangold+K%22">Mangold K</searchLink>; 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          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1