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Efficacy and safety of therapeutic alpha-1-microglobulin RMC-035 in reducing kidney injury after cardiac surgery: a multicentre, randomised, double-blind, parallel group, phase 2a trial.

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Title: Efficacy and safety of therapeutic alpha-1-microglobulin RMC-035 in reducing kidney injury after cardiac surgery: a multicentre, randomised, double-blind, parallel group, phase 2a trial.
Authors: Zarbock A; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Larsson TE; Guard Therapeutics International AB, Stockholm, Sweden., Noiseux N; Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada., Mazer CD; St. Michael's Hospital, University of Toronto, Toronto, Canada., Böhm J; Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, Technical University of Munich, Munich, Germany., Laflamme M; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada., Matschke K; Klinik für Herzchirurgie, Herzzentrum Dresden Universitätsklinik, Dresden, Germany., Burkert J; Fakultni Nemocnice v Motole, Prague, Czech Republic., de Varennes B; McGill University Health Centre - Royal Victoria Hospital, Montréal, Canada., Myjavec A; Department of Cardiac Surgery, Charles University, Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic., Böning A; Department of Cardiovascular Surgery, Justus-Liebig-University Giessen, Germany., Koyner JL; Section of Nephrology, University of Chicago, Chicago, IL, USA., Engelman D; Division of Cardiac Surgery, Baystate Medical Center, Springfield, MA, USA., Reusch M; Guard Therapeutics International AB, Stockholm, Sweden., Thielmann M; Klinik für Thorax- und Kardiovaskuläre Chirurgie, Westdeutsches Herz- und Gefäßzentrum Essen, Universität Duisburg-Essen, Germany.
Corporate Authors: AKITA investigators
Source: EClinicalMedicine [EClinicalMedicine] 2024 Sep 16; Vol. 76, pp. 102830. Date of Electronic Publication: 2024 Sep 16 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: The Lancet Country of Publication: England NLM ID: 101733727 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5370 (Electronic) Linking ISSN: 25895370 NLM ISO Abbreviation: EClinicalMedicine Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of therapeutic alpha-1-microglobulin RMC-035 in reducing kidney injury after cardiac surgery: a multicentre, randomised, double-blind, parallel group, phase 2a trial.
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